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The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Finasteride and analogues separated using LC-MS-MS technique.

Botox can effectively treat hair loss with some side effects and high cost, while LC hair serum also shows great results with fewer side effects.

LC-OCT is an effective new method for diagnosing classic lichen planopilaris.

LC-OCT is a promising tool for diagnosing and monitoring Alopecia areata.

Thymic LCH may be underdiagnosed, so thymic ultrasound should be considered in infants with cutaneous LCH.

Matrix effects in LC-MS can be managed but not completely avoided.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Only 40 nm nanoparticles can enter skin cells effectively for potential vaccine delivery.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Improved hair loss treatment using special particles and surfactants.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

Lack of Vitamin D receptor changes skin structure and increases certain immune cells in the skin.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.