April 2019 in “Journal of the Endocrine Society” In this case report, a 48-year-old woman's hyperandrogenism, presenting with symptoms like acne and hirsutism, was attributed to a benign Leydig cell tumor, which resolved after surgical removal.
The case showed the need for quick investigation of virilization in women and how emotional health is linked to physical health.
January 2019 in “Skin appendage disorders” This report presents a rare case where a bilateral ovarian thecoma in a postmenopausal woman led to an unusual pattern of female androgenetic alopecia mimicking male pattern hair loss.
November 2018 in “International Journal of Current Pharmaceutical Research” This review discusses the causes, underlying mechanisms, diagnosis, and treatment strategies for polycystic ovary syndrome but reports no new clinical findings.
November 2018 in “Endocrine Abstracts” A woman's high testosterone levels were caused by a rare ovarian tumor, not the initially diagnosed condition.
December 2010 in “Cancer Prevention Research” This study provides evidence supporting the feasibility of presurgical, window-of-opportunity models to evaluate the preventive potential of candidate agents in cancer, using cases from breast, prostate, and colorectal settings.
September 2010 in “European Urology Supplements” The document does not confirm if radical prostatectomy is the best treatment for locally advanced prostate cancer.
June 1995 in “International Journal of Gynecology & Obstetrics” This article discusses immunohistochemical analysis of estrogen and progesterone receptors in endometrium and peritoneal endometriosis, introducing a new quantitative method, but reports no new experimental results.
April 2020 in “Journal of The American Academy of Dermatology” This letter highlights concerns about transient lymphadenopathy as a potential adverse effect of platelet-rich plasma combined with microneedling for alopecia, emphasizing the need to understand its underlying cause.
January 2023 in “European journal of biology and medical science research” This review discusses the diverse prevalence, symptoms, and diagnostic criteria of Polycystic Ovary Syndrome in women and highlights that treatment varies based on symptom presentation and long-term management.
August 2019 in “Journal of Dermatology” This article is a letter to the editor discussing a rare case of Leydig cell tumor with type I diabetes mellitus causing female pattern hair loss, but it contains no abstract or new clinical findings.
25 citations
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September 2014 in “Biological Research” This study found that arctiin, a compound from Arctium lappa, demonstrated protective effects against oxidative stress-induced dysfunction in human hair dermal papilla cells, suggesting potential therapeutic use for alopecia.
19 citations
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March 2012 in “Journal of experimental botany” The researchers reported that in Arabidopsis collet hairs, nuclear positioning near the cell tip is not essential for hair growth, although it correlates with growth dynamics.
4 citations
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January 2019 in “Obstetrics & gynecology science” This case study reported that a 51-year-old woman with hirsutism and voice thickening had a Leydig cell tumor detected by PET-CT, which normalized hormone levels and resolved symptoms after surgical removal.
4 citations
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October 2013 in “Botanics Targets and Therapy” In this animal study, a herbal preparation demonstrated moderate anti-inflammatory and immunomodulating properties, suggesting its potential usefulness for preventing and treating alopecia.
4 citations
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December 2012 in “Arquivos Brasileiros De Endocrinologia E Metabologia” A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.
1 citations
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October 2024 in “BMJ Case Reports” This study highlighted that Sertoli-Leydig cell tumors should be considered in young women with secondary amenorrhea and virilization, and fertility-preserving surgery can be effective when diagnosed early.
1 citations
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August 2023 in “Case Reports in Women s Health” This case study in a 62-year-old postmenopausal woman highlights Leydig cell hyperplasia as a likely cause of hyperandrogenism of ovarian origin, where bilateral oophorectomy resolved the condition and confirmed the diagnosis through histopathological examination.
June 2025 in “Journal of Ovarian Research” This case report underlines the importance of considering alternative diagnoses like ovarian steroid cell tumors in adolescent females with PCOS-like symptoms when standard treatments fail, highlighting the need for thorough evaluation and early intervention.
June 2024 in “Deleted Journal” This review explored the potential of medicinal plants and natural compounds as alternative treatments for baldness, identifying several with anti-inflammatory and antioxidant properties that may help reduce hair loss.
October 2023 in “IJEM case reports” This case report describes the diagnosis and management of a 15-year-old girl with complete androgen insensitivity syndrome, highlighting the importance of thorough physical exams for early detection and treatment planning.
October 2023 in “Journal of the Endocrine Society” This case report describes a rare instance of hyperandrogenism and increased hirsutism associated with endometrial cancer in a postmenopausal woman, with symptoms resolving and androgen levels normalizing after a total laparoscopic abdominal hysterectomy and bilateral oophorectomy.
April 2021 in “Journal of Investigative Dermatology” In this study, researchers observed that different ERK signal activation dynamics during hair follicle regeneration are linked to cell fate specification and are affected by distinct upstream signaling pathways.
January 2020 in “대한미용학회지” This review discusses various natural substances used in scalp improvement cosmetics and reports their potential benefits, without providing new clinical results, and suggests more comprehensive studies are needed.
October 2014 in “Journal of Minimally Invasive Gynecology” Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.
January 2014 in “European Geriatric Medicine” A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
8 citations
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October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.
2 citations
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October 2015 in “The New England Journal of Medicine” This case report describes a 57-year-old woman with hirsutism, hair loss, and vocal changes, who was found to have elevated testosterone levels but normal dehydroepiandrosterone sulfate levels.
October 2012 in “The American Journal of Gastroenterology” This case report details a 21-year-old female diagnosed with a massive gastric trichobezoar due to trichophagia, successfully treated with single incision laparoscopic surgery and slated for psychiatric follow-up to prevent recurrence.
6 citations
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May 2022 in “Chemistry & biodiversity” This study identified compounds from Laportea bulbifera with potential inhibitory effects on human steroid 5α-reductase 2, suggesting their application in treating benign prostatic hyperplasia.