Rare Case of Leydig Cell Tumor with Type I Diabetes Mellitus Causing Female Pattern Hair Loss
August 2019
in “
Journal of Dermatology
”
TLDR Woman with diabetes had hair loss due to rare ovarian tumor; surgery improved hair growth.
A 54-year-old woman with type 1 diabetes mellitus (T1DM) and chronic kidney disease visited a dermatology department for frontal hair loss. She was diagnosed with female pattern hair loss (FPHL) and had a few recurrent acnes on her chin. Her serum testosterone levels were high, and pelvic MRI showed the presence of a left ovarian tumor that was 23 mm in diameter. The patient underwent laparoscopic bilateral salpingo-oophorectomy, and the tumor was identified as a Leydig cell tumor (LCT). Three months after the operation, her alopecia significantly improved, and serum testosterone levels were restored to normal levels. The findings of the case suggest that FPHL with LCT is associated with obesity, lifestyle diseases, T2DM, and T1DM.