Case 33-2015
October 2015
in “
The New England Journal of Medicine
”
hyperandrogenism hirsutism scalp hair loss ovarian hyperthecosis testosterone transvaginal ultrasonography endometrial biopsy robot-assisted laparoscopic total hysterectomy bilateral salpingo-oophorectomy alopecia dermatologist postmenopausal hyperandrogenism hair loss hair growth hysterectomy ovary removal
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TLDR The woman's surgery lowered her testosterone and improved scalp hair loss but did not change her excessive body hair.
The document detailed the case of a 57-year-old woman with symptoms of hyperandrogenism, including hirsutism, scalp hair loss, and a deepening voice, leading to a diagnosis of ovarian hyperthecosis. Elevated testosterone levels were noted, but imaging showed no tumors. Transvaginal ultrasonography and an endometrial biopsy supported the diagnosis, which was confirmed after a robot-assisted laparoscopic total hysterectomy and bilateral salpingo-oophorectomy. Post-surgery, the patient's testosterone levels decreased, and her alopecia mildly improved, but her hirsutism did not change. She was referred to a dermatologist for further symptom management. The document highlights that hirsutism typically does not revert after treatment for postmenopausal hyperandrogenism, but scalp hair growth usually recovers, and a more feminine body habitus is restored.