The Clinical Manifestations of Polycystic Ovary Syndrome and the Treatment Options

    Shilpa Karkera, Earlina Agard, Larysa Sankova
    From the encyclopedia
    Metformin →

    diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Studysummary This review discusses the diverse prevalence, symptoms, and diagnostic criteria of Polycystic Ovary Syndrome in women and highlights that treatment varies based on symptom presentation and long-term management.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder in women, particularly those aged 21-34, with a global prevalence ranging from 2.2% to 20%. Common symptoms include menstrual irregularities, hirsutism, weight gain, and insulin resistance. Diagnosis relies on three criteria: ovulatory dysfunction, hyperandrogenism, and polycystic ovaries, with the Rotterdam criteria being the most widely used. Treatment varies based on symptoms and includes Clomiphene Citrate, Letrozole, Oral Contraceptive Pills, and second-line therapies like Gonadotropins, Metformin, and Laparoscopic Ovarian Drilling for menstrual irregularities, and Finasteride, Isotretinoin, Spironolactone, and Flutamide for hyperandrogenism. Lifestyle modifications and weight reduction are also recommended.
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