February 2026 in “Andrology” This study highlights the need for a comprehensive andrological assessment at diagnosis, including semen and hormonal analysis, to guide fertility preservation strategies, and found that post-orchidectomy semen samples showed improved DNA integrity for assisted reproductive technologies.
January 2023 in “Journal of the College of Physicians and Surgeons Pakistan” This case report describes a 24-year-old woman with a stage IIIC retiform variant of Sertoli-Leydig cell tumour, highlighting the challenges in managing this rare ovarian tumour.
October 2012 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This case report describes a 57-year-old woman diagnosed with a Sertoli-Leydig cell tumor, whose progressive hair loss and high testosterone levels improved significantly following surgery.
September 2024 in “Electronic Journal of General Medicine” In this case series study, two Peruvian women with virilizing ovarian tumors called Sertoli-Leydig cell tumors showed clinical improvement and normalization of androgens after surgical treatment, highlighting the diagnostic challenge of these rare presentations at different ages.
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October 2014 in “Gynecological Endocrinology” This case study describes a 15-year-old girl with a Sertoli–Leydig cell tumor who showed high androgen levels and steroidogenic responses similar to patients with polycystic ovary syndrome before surgery.