Sertoli-Leydig Cell Ovarian Tumor: A Rare Cause of Virilization and Androgenic Alopecia

    August 2022 in “ Case Reports
    Sriram Mudraje, Sahana Shetty, Shyamala Guruvare, Ranjini Kudva
    TLDR A rare ovarian tumor caused high testosterone, hair loss, and missed periods, but surgery fixed these issues and led to pregnancy.
    A woman in her 30s presented with androgenic alopecia, virilisation, and secondary amenorrhoea, and was found to have extremely high testosterone levels. Imaging revealed a right ovarian mass, leading to a diagnosis of a testosterone-secreting Sertoli-Leydig cell tumour, a rare type of ovarian neoplasm. The patient underwent right salphingo-oophorectomy, which resulted in normalisation of serum testosterone levels, reduction in virilisation, and resumption of menstrual cycles. She conceived spontaneously 2 months post-surgery.
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