Sertoli-Leydig Cell Ovarian Tumor: A Rare Cause of Virilization and Androgenic Alopecia

    August 2022 in “ Case Reports
    Sriram Mudraje, Sahana Shetty, Shyamala Guruvare, Ranjini Kudva
    Studysummary This case report describes a woman in her 30s who had virilisation and androgenic alopecia due to a testosterone-secreting ovarian tumor, which normalized after its surgical removal.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    A woman in her 30s presented with androgenic alopecia, virilisation, and secondary amenorrhoea, and was found to have extremely high testosterone levels. Imaging revealed a right ovarian mass, leading to a diagnosis of a testosterone-secreting Sertoli-Leydig cell tumour, a rare type of ovarian neoplasm. The patient underwent right salphingo-oophorectomy, which resulted in normalisation of serum testosterone levels, reduction in virilisation, and resumption of menstrual cycles. She conceived spontaneously 2 months post-surgery.
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