82 citations
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August 2017 in “Cell Reports” This study found that antibiotic-induced gut dysbiosis, particularly overgrowth of Lactobacillus murinus, can lead to hair loss in mice by depleting biotin.
15 citations
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April 2020 in “Intestinal Research” This study observed that fecal microbiota transplantation for ulcerative colitis may also offer incidental benefits such as weight loss, improved hair loss, and relief from axial arthritis and allergic rhinitis.
10 citations
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May 2020 in “Dermatology Research and Practice” This review discusses "follicular hypoglycania" as a potential pathology in hair growth disorders and reports that proteoglycan replacement therapy may improve hair loss treatments, though it presents no new clinical trial results.
2 citations
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November 2023 in “Frontiers in microbiology” This review suggests that the gut microbiome and metabolome may play a significant role in alopecia areata and emphasizes the potential of targeting these factors for improved prevention, diagnosis, and treatment strategies for this skin condition.
November 2022 in “Journal of Education, Health and Sport” This review discusses the current understanding of the skin microbiome's potential influence on alopecia areata and emphasizes the need for further study, reporting no new experimental results.
June 2022 in “Research Square (Research Square)” This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischaemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and protecting intestinal mucosal function.
September 2020 in “Journal of Investigative Medicine” This article discusses the role of the microbiome in different forms of alopecia and highlights the importance of Omics approaches for future research, but it provides no new clinical results.
January 2026 in “Frontiers in Pharmacology” This study suggests that cedrol may improve mitochondrial function, gut microbiota, and intestinal barrier integrity, indicating its potential value in treating inflammatory bowel disease.
3 citations
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January 2021 in “Actas Dermo-Sifiliográficas” This review discusses the scalp and follicular microbiome's potential role in hair diseases and the emerging interest in microbiome-targeted therapies, but reports no new clinical findings.
July 2025 in “Scientific Reports” This study observed that serotonin signaling promoted hair shaft elongation and upregulated hair growth-related genes in dermal papilla cells, suggesting its potential role in advancing alopecia therapy.
October 2023 in “FASEB bioAdvances” This study investigated the effects of Akkermansia muciniphila on testosterone-induced hair growth inhibition in mice, finding that both live and pasteurized forms significantly encouraged hair growth and increased hair follicle size and growth factor levels compared to testosterone treatment alone.
227 citations
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April 2020 in “Cell” This review highlights the ongoing challenges and advancements in developing precise and early intervention strategies for autoimmune diseases and emphasizes the need for more personalized and disease-specific therapies.
40 citations
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September 2019 in “World journal of clinical cases” In this case report, an 86-year-old man experienced new hair growth and color change in alopecia areata after receiving fecal microbiota transplantation for noninfectious diarrhea.
6 citations
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December 2022 in “Cell reports” This study found that feeding mice a high-fat diet with fish oil leads to hair loss through a mechanism involving omega-3 fatty acids and TNF-α signaling, with epidermal fatty acid binding protein playing a key role.
6 citations
,
October 2022 in “Frontiers in Cell and Developmental Biology” This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and enhancing intestinal stem cell expression.
6 citations
,
January 2020 3 citations
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August 2024 in “Frontiers in Endocrinology” This study offers genetic evidence supporting a causal relationship between thyroid dysfunction and alopecia areata, which may help in managing and treating AA patients.
1 citations
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March 2023 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses recent advances in understanding and treating alopecia areata, emphasizing the ongoing challenges and unmet needs in disease management; it reports no new clinical findings.
1 citations
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April 2022 in “BMC Genomics” This study reported that alopecia in giant pandas may be linked to abnormal expression of several hair-related genes and pathways, providing insight for potential prevention and treatment strategies.
July 2026 in “Pharmaceuticals” This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.
February 2026 in “Probiotics and Antimicrobial Proteins” Modifying gut bacteria with pro- and postbiotics may help treat hair loss.
In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.
November 2024 in “Journal of Clinical Medicine” This study observed that six sessions of injections using a stabilized hyaluronic acid compound improved hair thickness, shine, density, and reduced hair loss in volunteers with moderate androgenetic alopecia, with excellent treatment tolerability and high satisfaction reported by 88.5% of participants.
August 2024 in “Pharmaceuticals” This study found that oral administration of solubilized sturgeon oil in mice promoted hair growth and positively influenced the gut microbiome associated with hair growth promotion.
August 2024 in “Food Bioscience” This study reported that in laboratory conditions, a cell-free supernatant of Bifidobacterium longum BB536 promoted human dermal papilla cell proliferation and reduced damage and apoptosis caused by dihydrotestosterone, suggesting potential use as a preventative treatment for androgenic alopecia by modulating specific signaling pathways.
April 2024 in “Frontiers in microbiology” This study found that certain gut microbiota are linked with androgenetic alopecia, identifying both risk and protective microbial factors, which could inform targeted probiotic strategies for managing AGA.
December 2022 in “Frontiers in Microbiology” This study found that individuals with androgenetic alopecia had higher scalp microbiome diversity and more complex scalp-gut microbiome networks than those without, suggesting a link between skin-gut microorganisms and hair loss development.
26 citations
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September 2023 in “Bioengineered” This review article discusses recent progress in the extraction and potential health benefits of oligosaccharides from brown seaweeds, especially focusing on their antimicrobial, anti-inflammatory, and prebiotic properties, and possible applications in managing metabolic syndrome.
12 citations
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June 2011 in “Han-guk sikpum gwahakoeji/Han'gug sigpum gwahag hoeji/Han-guk sikpum gwahak hoeji” This study found that MBN, an herbal extract fermented by Lactobacillus plantarum, promoted hair growth and increased related gene expression in C57BL/6 mice.
10 citations
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April 2019 in “Journal of Analytical Science and Technology” In this study, hydrolysates of lactic acid bacteria were found to enhance hair growth in C57BL/6 male mice more effectively than 5% minoxidil.