139 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.
July 2009 in “Planta Medica” This survey in Pabna district, Bangladesh, documented various plants used by traditional healers for treating ailments, highlighting regional variations in plant usage.
8 citations
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March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
24 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers identified two new keratin-associated proteins, hKAP1.6 and hKAP1.7, in human hair follicles, contributing to understanding hair fiber differentiation.
1 citations
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September 2023 in “Genes” This study found no significant difference in CUX1 core promoter methylation levels between different lambskin patterns in Hu sheep, suggesting other mechanisms influence CUX1 expression related to hair follicle development.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that many participants with hair loss, or Khalitya, exhibited dietary incompatibilities and low calcium levels, aligning Ayurvedic concepts with modern dietary risk factors.
January 2025 in “International journal of Indian medicine” This review discusses nine Ayurvedic medicinal herbs listed in the Dhanvantari Nighantu as beneficial for hair, detailing their properties like promoting hair growth, enhancing hair thickness, and maintaining dark hair color, alongside supporting research on these effects.
15 citations
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September 2002 in “Journal of Biological Chemistry” This study observed that transgenic mice expressing keratin K10 under bovine K6beta control developed severe oral abnormalities, suggesting keratin composition changes can affect the physiology of epithelial cells, especially in the oral mucosa.
October 2025 in “Indian Dermatology Online Journal” This study explored how using kitchen-related analogies for dermatological signs, like comparing certain appearances to common culinary items, can enhance understanding and retention of complex medical concepts in dermatology.
32 citations
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January 2020 in “Journal of Molecular Histology” This research identified K31 as a new marker for distinguishing clear secretory cells in human eccrine sweat glands, aiding in differentiating between distinct cell types within these glands.
July 2019 in “International journal of Unani and integrative medicine” This paper reviews classical Unani texts and scientific research on Cuscuta reflexa, covering its traditional uses and pharmacological properties, but presents no new clinical results.
62 citations
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified 16 novel high sulfur KAP genes and two KAP pseudogenes on chromosome 21q23, showing expression in a specific region of the hair fiber cuticle.
February 2026 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” This study found that cis-urocanic acid can engage in non-enzymatic reactions with reactive sulphur species, forming new metabolites, and suggests sulphide donors may protect against UVB-related toxicity.
May 2026 in “International Research Journal of Ayurveda & Yoga” This review explores the Charaka samhita's concept of Ashtanindita purusha, identifying eight physical constitutions traditionally regarded as undesirable due to their association with various diseases, and aims to correlate these with contemporary genetic, endocrinological, and metabolic disorders.
2 citations
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February 2021 in “FEBS open bio” In this study, transfection experiments showed that mutations in the K85 gene affect filament formation with K35, which may impact hair formation related to ectodermal dysplasia.
March 2026 in “Journal of Ayurveda and Integrative Medicine” This study found that the Sonowal Kachari tribe in Assam, India, utilizes 39 plant species for medicinal purposes, with leaves being the most commonly used part, highlighting the tribe's substantial traditional knowledge of herbal medicine.
32 citations
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April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This study demonstrates that keratin K2 is crucial for proper keratinocyte structure and function in specific mouse skin areas, and its deficiency leads to cellular aggregates and skin abnormalities.
1 citations
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May 2004 in “Biochemical and Biophysical Research Communications” This study identified nine novel KRTAP5 family genes associated with human hair formation, demonstrating preferential expression in hair roots and suggesting their role in hair development.
February 2013 in “Archives of Disease in Childhood Education & Practice” This text describes kerion, a severe form of tinea capitis, and emphasizes the difficulty of diagnosis and the need for oral antifungal treatment, but reports no new clinical results.
130 citations
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April 2003 in “Journal of Investigative Dermatology” This study reports the cloning and expression details of two new human type II keratins, K6irs3 and K6irs4, in the hair follicle's inner root sheath, suggesting a distinct functional role related to hair structure.
January 2026 in “International Journal of Scientific Research in Science and Technology” This study highlights the prevalence of hair loss in India, with over half the population experiencing hair fall or baldness, and discusses Ayurvedic approaches for managing these conditions according to different ancient texts.
January 2024 in “International Ayurvedic medical journal” This study explores how Ayurveda concepts, specifically Prakruti, relate to male pattern baldness, suggesting that individual constitutional types may predict susceptibility to earlier hair loss when influenced by modern lifestyle factors.
27 citations
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April 2004 in “Biochemical and Biophysical Research Communications” In this study, two novel clusters of keratin-associated protein genes on human chromosome 11 were analyzed, suggesting their products are crucial for hair formation due to preferential expression in hair roots.
January 2024 in “Animals” This study suggests that the transcription factors SP1 and KROX20 regulate CUX1 gene's effect on the proliferation of ovine dermal papilla cells in vitro.
38 citations
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October 2001 in “British Journal of Dermatology” This study identified a new keratin, K6irs, as a potential histological marker for the inner root sheath of hair follicles in mice and humans, and as a candidate gene for hereditary hair defects.
35 citations
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October 2002 in “Biochemical and Biophysical Research Communications” This study reports that K7 expression patterns observed in mice are similar to those in humans, revealing previously unreported expression in the gastrointestinal tract, tongue, and various "hard" epithelial tissues.
38 citations
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December 2006 in “Journal of Investigative Dermatology” Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.
November 2022 in “Journal of Investigative Dermatology” This study found that DermaCult™ Keratinocyte Expansion Medium allows for significantly extended growth of human epidermal keratinocytes while maintaining their differentiation potential.
August 2023 in “International Ayurvedic medical journal” In this thesis, the authors concluded that various lifestyle factors such as poor dietary habits, stress, and inadequate hair care habits contribute significantly to hair fall, or Khalitya, highlighting the role of lifestyle changes in mitigating hair loss.