research Metabolic Teamwork in the Stem Cell Niche
Paneth cells and intestinal stem cells work together metabolically for stem cell function and regeneration.
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research News in Brief
Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.
research Non-Canonical Wnt Signaling Promotes Directed Migration of Intestinal Stem Cells to Sites of Injury
Special gut cells help stem cells move to and fix injured areas by activating a specific signaling pathway.
research Tailored Chromatin Modulation to Promote Tissue Regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organs
Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
research Valproic Acid and/or Rapamycin Preconditioning Protects Hair Follicle Stem Cells from Oxygen Glucose Serum Deprivation-Induced Oxidative Injury via Activating Nrf2 Pathway
Valproic acid and rapamycin protect hair follicle stem cells from damage by activating a protective pathway.
research Review of Factors Affecting the Growth and Survival of Follicular Grafts
Optimal storage solutions and effective additives are crucial for improving the survival of hair transplant grafts.
research Alopecia Areata: A Review of the Role of Oxidative Stress, Possible Biomarkers, and Potential Novel Therapeutic Approaches
Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.
research Ganoderma Lucidum Extract Attenuates Corticotropin-Releasing Hormone Induced Cellular Senescence in Human Hair Follicle Cells
Ganoderma lucidum extract may help treat stress-related hair loss.
research Forsythiaside A Protects Against Focal Cerebral Ischemic Injury by Mediating the Activation of the Nrf2 and Endoplasmic Reticulum Stress Pathways
Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.
research A Desmosomal Cadherin Controls Multipotent Hair Follicle Stem Cell Quiescence and Orchestrates Regeneration Through Adhesion Signaling
A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
research Reversible Alopecia with Localized Scalp Necrosis After Accidental Embolization of the Parietal Artery with Hyaluronic Acid
Accidental injection of hyaluronic acid caused temporary hair loss and skin damage, but treatment restored hair and healed the skin.
research Complications of Mesotherapy
Mesotherapy can cause serious side effects like infections and skin reactions.
research Postoperative Pressure Alopecia in a Child Following the Use of a Gel Horseshoe Head Pad
Using a gel head pad during surgery can cause hair loss in children.
research BCL-2 and Bax Expression in Skin Flaps Treated with Finasteride or Azelaic Acid
Azelaic acid and finasteride can help preserve skin flaps after surgery by increasing BCL-2 protein and decreasing bax protein.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
research Carbon, Nitrogen, And Sulfur Elemental And Isotopic Variations In Mouse Hair And Bone Collagen During Short-Term Graded Calorie Restriction
Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.
research Reframing Filler-Induced Alopecia: Recognizing Pressure Alopecia as a Distinct Mechanism in Injectable Complications
Pressure from injectable treatments can cause hair loss by compressing blood vessels.
research Therapeutic Potential of Hair Follicle-Derived Stem Cell Intranasal Transplantation in a Rat Model of Ischemic Stroke
Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
research Identification of an Osteopontin-Derived Peptide That Binds Neuropilin-1 and Activates Vascular Cells
FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
research Ischemic Vaso-Occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
Early treatment of pediatric lupus-related eye issues is crucial to prevent vision loss.
research The Role of Ischemia-Modified Albumin and Ischemia-Modified Albumin to Albumin Ratios in Patients with Alopecia Areata
IMA and IMA/albumin levels don't predict alopecia areata severity.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
EGFR helps control how hair grows and forms without needing p53 protein.
research Ischemic Skin Flaps: What to Use to Save Them? A Narrative Review
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.
research Hormonal, Medical, and Nonsurgical Aspects of Gender Affirmation
The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.
research Cardiovascular Risk in Patients with Selected Cutaneous Diseases
Skin diseases like psoriasis, lupus, and others can increase heart disease risk due to factors like chronic inflammation and genetic susceptibility.
research Post-Operative Alopecia of the Scalp: A Rare Complication Following Shoulder Surgery
A woman's hair grew back within 3 months after temporary hair loss from improper head positioning during shoulder surgery.
research Improving Translational Research in Sex-Specific Effects of Comorbidities and Risk Factors in Ischemic Heart Disease and Cardioprotection: Position Paper and Recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
research Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by Increasing Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps
IL-6 from stem cells helps repair skin and grow hair.