Ischemia-Modified Albumin: A Potential New Marker of Oxidative Stress in Dermatological Diseases

    May 2022 in “ Medicina-lithuania ”
    Mircea Tampa, Cristina Iulia Mitran, Mădălina Irina Mitran, Andreea Amuzescu, Clara Matei, Simona Roxana Georgescu
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    TLDR IMA may indicate oxidative stress in skin and hair disorders, but more research is needed.
    The document reviews 24 original articles that evaluated ischemia-modified albumin (IMA) as a potential marker of oxidative stress in various dermatological diseases, including skin disorders like psoriasis, acne vulgaris, and vitiligo, and hair disorders such as alopecia areata and androgenetic alopecia. The majority of these studies found higher IMA levels in patients compared to control groups, suggesting that IMA could be a marker of oxidative stress. However, the correlation between IMA levels and disease severity or duration is not conclusive. The document concludes that further research with larger participant numbers is needed to fully understand the potential biological implications of IMA in dermatological diseases.
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