Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reports that in women with non-tumor hyperandrogenism, a decrease in serum testosterone from insulin-sensitizing therapy like metformin may indicate a low likelihood of having an androgen-secreting tumor.

This study found that topical cepharanthine increased IGF-I production in human dermal papilla cells, suggesting it may stimulate hair growth and be a promising treatment option for androgenetic alopecia.

This study identified certain benzopyran derivatives with a bulky tert-butyloxycarbonylamino group as effective KATP channel openers that inhibit insulin secretion in rat pancreatic islets.

This study observed that insulin-dependent diabetes induces specific molecular changes in the keratin structure of hair, potentially offering a new way to study diabetic complications through easily accessible tissues.

Tirzepatide may improve hair loss by reducing insulin resistance.

This study suggests that genetic variations in the AMH signal pathway may be linked to susceptibility and phenotype variations in PCOS among women with insulin resistance.

This study found that women with PCOS had significantly higher angiotensin converting enzyme activity and insulin resistance compared to controls, suggesting a correlation between these factors.

This study suggests that some men with premature androgenic alopecia may have hormonal profiles similar to women with polycystic ovary syndrome, potentially indicating a male equivalent of the condition.

This study suggests that insulin levels may influence ovarian volume in women with idiopathic hirsutism who have normal ovulatory cycles and androgen levels.

This study highlights the need to prioritize early prevention of type 2 diabetes mellitus by focusing on early pathophysiologic mechanisms such as insulin resistance, rather than hyperglycemia, as conditions like non-alcoholic fatty liver disease and polycystic ovarian syndrome are early indicators of future diabetes risk.

This study found that higher Lnk expression in PCOS patients may contribute to insulin resistance by inhibiting insulin signaling pathways.

In this study, the prevalence of insulin resistance in reproductive-aged Thai women with polycystic ovary syndrome was found to be 20%, with age, waist circumference, acanthosis nigricans, and dyslipidemia as significant predictors.

In this study, the researchers found distinct patterns of TGF-beta 1 and IGF-II expression in pig fetal subcutaneous tissue, suggesting specific regulatory roles in developing adipocytes and muscle tissue.

This study suggests that the gene rs27647 polymorphism may play a role in the pathogenesis of severe acne vulgaris in post-adolescent male patients.

This study found that male patients with early-onset androgenetic alopecia were associated with metabolic syndrome, but not insulin resistance, compared to age-matched controls.

This study found that 1,550-nm Er:Glass fractional laser treatment increased hair density and shaft diameter in patients with androgenetic alopecia, but did not up-regulate Wnt10A and IGF-1 mRNA expression.

This study found a significant association between the IRS-2 gene variant and an increased risk of PCOS, especially in non-obese women in the Chinese population from Taiwan.

This study found that combining low-dose spironolactone with metformin improved insulin resistance in PCOS patients more effectively than using either drug alone.

Among cultured sebocytes, this study found that bilobetin significantly inhibited lipid production induced by IGF-1, suggesting potential for use in acne treatment.

This study found that Greek women with classic PCOS phenotypes have a higher risk of metabolic syndrome and impaired glucose homeostasis compared to those with newer PCOS phenotypes.

This case report indicates that HAIR-AN syndrome can lead to severe hyperandrogenism with virilisation signs in women after excluding tumoral causes and identifying signs of insulin resistance.

In this study, insulin resistance was observed at similar rates in non-obese women with idiopathic hirsutism, those with PCOS, and healthy controls.

This study found that women with androgenetic alopecia were more insulin resistant than healthy controls, suggesting the use of beta cell function and insulin sensitivity indices to measure insulin resistance in this population.

This study found that the INSR His1058 C/T SNP does not increase the risk of developing PCOS among Kashmiri women.

This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.

This study found that metformin treatment improved clinical outcomes in Taiwanese women with polycystic ovary syndrome, notably in overweight and insulin-resistant patients.

This study reports that low levels of HDL cholesterol and IGF-1 were associated with a higher risk of hair loss in middle-aged women, but causal relationships remain uncertain.

This study found that acanthosis nigricans and skin tags in nondiabetic, obese patients were significantly associated with higher insulin levels, suggesting they may serve as clinical markers of hyperinsulinemia.

In this study, topical tacrolimus 0.1% ointment applied to mice skin decreased Vegf and Igf-1 mRNA levels during late anagen but did not alter hair cycling or skin appearance compared to untreated skin.

This paper explores the mechanisms causing depression in women with PCOS and suggests that lifestyle modifications, such as dietary changes and weight loss, as well as cognitive behavioral therapy and antidepressants, can help manage PCOS-induced depression.