Association Between Ovarian Volume and Serum Insulin Levels in Ovulatory Patients with Idiopathic Hirsutism

    May 2005 in “ Fertility and Sterility ”
    Renato Frajndlich, Poli Mara Spritzer
    TLDR Higher insulin levels are linked to larger ovaries in women with idiopathic hirsutism.
    The study examined 45 women with idiopathic hirsutism and regular ovulatory cycles, finding that those with larger ovarian volumes (>9 cm³) had higher insulin levels, insulin-to-glucose ratios, and HOMA scores. A positive correlation (r = 0.37, P = .02) between insulin levels and ovarian volume was observed, indicating that insulin might influence ovarian size independently of BMI or LH/FSH ratio. The findings suggested that insulin could be a key factor in determining ovarian volume in these patients, warranting further research to understand the clinical implications.
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