Association Between Ovarian Volume and Serum Insulin Levels in Ovulatory Patients with Idiopathic Hirsutism

    May 2005 in “ Fertility and Sterility
    Renato Frajndlich, Poli Mara Spritzer
    TLDR Higher insulin levels are linked to larger ovaries in women with idiopathic hirsutism.
    In a study of 45 women with idiopathic hirsutism and regular ovulatory cycles, it was found that those with larger ovarian volumes (>9 cm³) had significantly higher insulin levels, insulin-to-glucose ratios, and HOMA scores compared to those with smaller ovaries. A positive correlation between insulin levels and ovarian volume was observed, independent of BMI or LH/FSH ratio, suggesting that insulin may play a role in increasing ovarian volume in these women.
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