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30-60 / 1000+ results![Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways](/images/research/e0d89d25-c3c0-4397-8ce3-4140ea71f8cb/small/4135.jpg)
research Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
![BMP2 and BMP7 play antagonistic roles in feather induction](/images/research/4d818cdd-ce31-4dda-a2ce-631700217e20/small/35654.jpg)
research BMP2 and BMP7 play antagonistic roles in feather induction
BMP2 and BMP7 have opposite roles in feather formation.
![Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells](/images/research/5d79073c-ee83-4175-a460-1c2d10e8e93f/small/19280.jpg)
research Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
Muscles and nerves that cause goosebumps also help control hair growth.
![Hair follicle stem cells isolated from newborn Yangtze River Delta White Goats](/images/research/69906114-fc93-45a2-991b-17c99c4561e4/small/29028.jpg)
research Hair follicle stem cells isolated from newborn Yangtze River Delta White Goats
Researchers found a good way to isolate hair follicle stem cells from newborn goats for further study.
![The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis](/images/research/507008ab-9a3f-40a0-aabe-a00697f832c1/small/35061.jpg)
research The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
![Hair follicle stem cell progeny heal blisters while pausing skin development](/images/research/6a0ad6bf-533d-477b-8b06-4e66d818e02e/small/30830.jpg)
research Hair follicle stem cell progeny heal blisters while pausing skin development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
![Transforming growth factor-β in stem cells and tissue homeostasis](/images/research/4d38f480-144e-4334-af2c-4d1b50204625/small/19469.jpg)
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
![Hair follicle stem cells: Walking the maze](/images/research/f0e5a327-4ce3-481e-99c9-e62bc6945e29/small/12873.jpg)
research Hair follicle stem cells: Walking the maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
![Anatomy and Function of the Skin](/images/research/3ac1fb84-b45e-4b82-960d-dac3f4669924/small/34901.jpg)
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
![Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies](/images/research/3a7f4f5e-d917-43b9-a998-f3339717049a/small/30922.jpg)
research Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
![Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas](/images/research/7f84ac19-edba-44df-9c53-d2cefa5b7246/small/20933.jpg)
research Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas
The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
![Epithelial Cells in the Hair Follicle Bulge do not Contribute to Epidermal Regeneration after Glucocorticoid-Induced Cutaneous Atrophy](/images/research/050de2ee-8750-4f7b-b399-1ab68b88d701/small/27810.jpg)
research Epithelial Cells in the Hair Follicle Bulge do not Contribute to Epidermal Regeneration after Glucocorticoid-Induced Cutaneous Atrophy
Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
![Defining the Localization and Molecular Characteristic of Minor Salivary Gland Label-Retaining Cells](/images/research/7a00d7b3-4aea-47ef-86b7-145ce38940e4/small/34049.jpg)
research Defining the Localization and Molecular Characteristic of Minor Salivary Gland Label-Retaining Cells
The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
![Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice following Topical Application of Fluocinolone Acetonide](/images/research/1bc89236-c519-42e0-9512-d9d0238652cb/small/19970.jpg)
research Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice following Topical Application of Fluocinolone Acetonide
Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.
![Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation](/images/research/d4cdf821-33bb-49dc-9157-ed78bab6f0ca/small/35652.jpg)
research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation
Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
![Compartmentalized organization: a common and required feature of stem cell niches?](/images/research/1174f84f-0748-4a94-804a-aba5100f35f3/small/19908.jpg)
research Compartmentalized organization: a common and required feature of stem cell niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
![Dynamic Signals for Hair Follicle Development and Regeneration](/images/research/e842b782-08fc-498a-966e-a0da144707fb/small/12849.jpg)
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
![Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells](/images/research/ae7a95a3-f466-4f8b-9387-ea33cfaf32ec/small/34077.jpg)
research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells
Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
![Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth](/images/research/e0401d53-9d74-4685-a2d0-efa6d60a1381/small/34028.jpg)
research Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth
The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
![Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles](/images/research/69bff0a0-ffb1-4db6-ba2d-2adef27e908e/small/34080.jpg)
research Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles
Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
![Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration](/images/research/4dc60f0c-0d69-4d1f-bd80-cfcbf0072e5d/small/19235.jpg)
research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
![Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages](/images/research/35cf3a6b-4b57-42f2-afda-acddd94fd699/small/19722.jpg)
research Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages
The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
![Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development](/images/research/24659c07-f6f8-42ec-9e92-f8035876e064/small/19297.jpg)
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
![DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch flox/flox CD4Cre +/− Mice](/images/research/2350e4cb-21e3-49c9-840d-20798d2e4bb1/small/19714.jpg)
research DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch flox/flox CD4Cre +/− Mice
Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
![Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response](/images/research/23c7f30e-d474-4600-9378-9b891e8c7327/small/19511.jpg)
research Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
![A guide for building biological pathways along with two case studies: hair and breast development](/images/research/dda2b529-6c76-4105-869f-e297ff27ee19/small/35630.jpg)
research A guide for building biological pathways along with two case studies: hair and breast development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
![Stem Cells in the Skin](/images/research/14fee45f-7d2c-4af6-aeeb-bcaf12af2105/small/19587.jpg)
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation
Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.