23 citations,
March 1994 in “Fertility and sterility” Most patients improved with oral contraceptives, but some needed additional treatment.
6 citations,
August 2005 in “The Journal of Clinical Endocrinology & Metabolism” Finasteride causes temporary cell death in BPH tissues.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles have a unique way of using energy and might use the Cori cycle; blocking CCR5 could help treat hair loss.
15 citations,
July 2012 in “Biological trace element research” Higher hair calcium to magnesium ratios and lower chromium levels in hair may indicate insulin resistance in Korean men.
January 2024 in “Journal of the Endocrine Society” The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.
31 citations,
January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
10 citations,
April 2000 in “Archives of Oral Biology” Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
25 citations,
May 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
10 citations,
November 2015 in “Plant Foods for Human Nutrition” Hibiscus petals helped control blood sugar and improve liver and pancreas health in diabetic rats.
January 2014 in “S. Karger AG eBooks” Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.
25 citations,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
5 citations,
March 2023 in “Archives of dermatological research” Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
74 citations,
July 2010 in “The Journal of Clinical Endocrinology & Metabolism” Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.
11 citations,
January 2020 in “Medical Journal Armed Forces India” Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
200 citations,
August 2009 in “Experimental dermatology” Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
September 2023 in “The FASEB journal” Foxn1 is important for fat development, metabolism, and wound healing in skin.
April 2019 in “Journal of the Endocrine Society” Androgens and estrogens are crucial for insulin secretion in males.
18 citations,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
12 citations,
May 2005 in “Fertility and Sterility” Higher insulin levels are linked to larger ovaries in women with idiopathic hirsutism.
6 citations,
April 2014 in “European journal of medicinal chemistry” New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
2 citations,
January 2019 in “Egyptian Journal of Dermatology and Venereology” Insulin might be involved in causing hair loss and acne.
1 citations,
January 2022 in “Journal of experimental and clinical medicine” PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
February 2024 in “Bioengineering” The hydrogel made of chitosan, HPMC, and insulin speeds up wound healing and could be a new dressing, especially for diabetics.
August 2015 in “Postgraduate obstetrics & gynecology” Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.
August 2015 in “Postgraduate obstetrics & gynecology” Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.
The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
February 2023 in “Clinical, Cosmetic and Investigational Dermatology” Higher leptin and lower vitamin D levels may contribute to male pattern baldness.
March 2022 in “Benha Journal of Applied Sciences” AGA patients have higher insulin resistance and serum progranulin levels, suggesting a link to metabolic issues.