16 citations
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January 2021 in “International Journal of Medical Sciences” This study found that gelatin microspheres loaded with platelet-rich plasma enhanced wound healing in rats by improving inflammatory and angiogenic responses compared to untreated wounds or PRP alone.
16 citations
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July 2018 in “Dermatologic Surgery” In this study, iL-PRF injections produced significantly better clinical scores for androgenetic alopecia patients compared to controls, especially in those with more severe baseline conditions.
15 citations
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January 2021 in “Journal of Materials Chemistry B” In this study, shear-thinning silk nanofiber hydrogels were found to enhance retention of mesenchymal stem cells and accelerate wound healing in rat models.
13 citations
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January 2017 in “Plastic and reconstructive surgery. Global open” This study found that Juvéderm Ultra Plus was safe and effective for correcting severe nasolabial folds in a Chinese population, requiring less volume than Restylane while achieving similar responder rates, with fewer severe treatment site reactions.
11 citations
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July 2024 in “Biomimetics” This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.
6 citations
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May 2024 in “Macromolecular Bioscience” This study synthesized a temperature-sensitive hydrogel with strong antibacterial capabilities against S. aureus and E. coli, demonstrated via in vitro and in vivo tests, suggesting potential for antibiotic-free clinical applications when activated by near-infrared light.
6 citations
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August 2016 in “Journal of women & aging” This study found that women with negative or mixed feelings about Botox and facial fillers reported diverse and sometimes persistent physical and psychological impacts, feeling commodified, fractured, abandoned, reflective, and transformed.
5 citations
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July 2023 in “World Journal of Stem Cells” In a study using a rat model, researchers developed injectable hydrogels from antler reserve mesenchyme which enhanced regenerative healing of full-thickness cutaneous wounds by creating a fetal-like niche that increased stem cell presence and modulated gene expression related to wound healing.
4 citations
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April 2024 in “Cellular and Molecular Biology” In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.
2 citations
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June 2023 in “Gels” This study highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research, emphasizing their roles in controlled drug delivery, tissue regeneration, and treatment of various conditions, such as cardiac issues, joint diseases, and bone regeneration.
2 citations
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October 2021 in “Experimental Cell Research” This study found that injectable platelet-rich fibrin (i-PRF) enhances hair follicle regeneration in vitro by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity, with varying effects depending on concentration.
1 citations
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May 2011 in “Hair transplant forum international” This article discusses the potential of platelet rich plasma injections for treating hair loss but reports no new clinical results, emphasizing the need for further research.
July 2025 in “Journal of Investigative Dermatology” AI-09 is safe, effective, and reduces wrinkles for up to 6 months.
March 2024 in “Journal of drugs in dermatology” This study evaluated the safety and effectiveness of HASHA, a new hyaluronic acid injectable, for chin augmentation in adults with chin retrusion. HASHA significantly improved chin appearance and satisfaction over 12 months compared to controls, with only mild or moderate transient adverse events.
June 2026 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” This study found that a hydrogel made from human placenta-derived ECM, copper, and endothelial progenitor cells significantly enhanced pressure ulcer healing in a mouse model by improving wound closure and tissue regeneration.
May 2026 in “International Journal of Biological Macromolecules” In this study, researchers developed a biomacromolecular hydrogel to deliver plant-derived extracellular vesicles for treating androgenetic alopecia in a mouse model, which significantly improved hair regrowth and follicle density by activating Wnt/β-catenin signaling.
April 2026 in “Journal of Dermatological Treatment” This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.
February 2026 in “MDPI (MDPI AG)” This review provides a comprehensive look at injectable treatments like PRP, stem cells, and exosomes for hair regrowth, highlighting their potential to minimize systemic and localized side effects associated with conventional medications, and improve patient care by stimulating natural hair growth.
February 2026 in “Journal of Aesthetic Nursing” This study reviewed evidence on injectable regenerative treatments for female pattern hair loss, finding that while PRP consistently improves hair density and thickness, the impact of such treatments on psychological wellbeing remains unclear, and patient-reported outcomes are inconsistently assessed.
January 2026 in “Dermatologic Surgery” In this systematic review, researchers found that injectable therapies, including agents like dutasteride and multivitamin formulations, may offer cosmetic benefits for androgenetic alopecia; however, evidence is limited by small study sizes, varied methods, and short follow-up periods, necessitating standardized trials for routine use recommendations.
December 2025 in “Journal of Pharma Insights and Research.” This paper reviews the state of knowledge on injectable cryogels, highlighting their unique properties such as shape-memory and mechanical integrity, which allow for minimally invasive delivery via needles and potential applications in oncology and regenerative medicine.
December 2025 in “Aesthetic Cosmetology and Medicine” This study reported that platelet-rich fibrin (iPRF) therapy may improve scalp health and hair appearance in women, showing beneficial changes in scalp hydration, redness, oiliness, and hair density, thickness, and loss.
November 2025 in “Scientia Pharmaceutica” This review highlights that injectable biostimulatory agents like poly-L-lactic acid, polycaprolactone, and calcium hydroxyapatite are effective in regenerative aesthetics by enhancing collagen production, stimulating adipogenesis, and improving dermal quality, although further research is needed to standardize protocols and confirm long-term safety and efficacy.
October 2025 in “Advanced Healthcare Materials” In a study on wound healing, researchers described injectable POEGMA‐DA hydrogels as a promising non-toxic alternative to traditional wound closure methods, showing effective tissue adhesion and enhanced regeneration of skin structures in a mouse model without significant inflammation.
June 2025 in “Journal of medical and dental science research.” This article explores the potential of platelet-rich fibrin therapies for androgenetic alopecia and highlights their possible advantages over traditional treatments without reporting new clinical results.
May 2025 in “Journal of medical and dental science research.” This article discusses the potential role and mechanisms of platelet-rich fibrin therapies in androgenetic alopecia management, exploring their possible benefits over existing treatments but reports no new clinical results.
March 2025 in “Archives of Dermatological Research” This source explores injectable minoxidil as a hair loss treatment, noting its enhanced bioavailability but also the potential for adverse effects and higher costs compared to other formulations, with a call for further research on its efficacy and access relative to alternatives.
February 2025 in “Archives of Dermatological Research” In this study, researchers administered injectable platelet-rich fibrin (i-PRF) to 30 patients with androgenetic alopecia, finding an 80% response rate after 6 months, with improved hair density and reduced scalp symptoms, while reporting minimal adverse reactions.
January 2025 in “Annals of dental specialty” This study found that Aloe Vera, injectable platelet-rich fibrin (i-PRF), and their combination affected the proliferation of mesenchymal stem cells derived from human hair follicles, with varying concentrations tested for proliferation and cytotoxic effects.
December 2024 in “Research Journal of Medical Sciences” Injectable Platelet Rich Fibrin effectively improves hair growth in males with hair loss.