Advances in Medicalized Hair Loss Solutions: A Review of Current Clinical Practices and Regenerative Medicine-Based Protocols with Focus on Off-Label Injectable Treatments

February 2026 in “ MDPI (MDPI AG) ”

Angelica Ferro, Mansour Alsoghair, Alexandre Porcello, Marco Cerrano, Michèle Chemali, Kelly Lourenço, Cíntia Marques, Wassim Raffoul, Lee Ann Applegate, Alexis Laurent

platelet-rich plasma stem cells exosomes hair follicles minoxidil finasteride injectable treatments regenerative medicine PRP Rogaine Propecia

TLDR Emerging injectable treatments like PRP, stem cells, and exosomes show promise for safer, more effective hair growth.

This review highlights the advancements in medicalized hair loss solutions, focusing on off-label injectable treatments like PRP, stem cells, and exosomes. These emerging therapies offer promising alternatives to conventional treatments by minimizing systemic side effects and localized adverse events. The review evaluates clinical studies on the efficacy and safety of these injectables, emphasizing the importance of injection techniques and administration protocols. These therapies aim to reactivate hair follicles for sustained and natural hair growth, providing more effective and durable solutions with improved safety profiles compared to traditional treatments like minoxidil and finasteride.

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