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This study found that newly developed nanogels for transdermal delivery of finasteride were stable, showed excellent drug permeation through the skin, and ensured biocompatibility without causing irritation or toxicity.

This narrative review emphasizes the significant improvements in mental well-being linked to gender-affirming treatments while highlighting the need for ongoing research into hormone therapy's long-term effects and its impact on transgender individuals' reproductive health.

This review discusses the role of athletic trainers in the medical affirmation and care of transgender and gender-diverse individuals, but it reports no new research findings; the authors emphasize the need for interprofessional collaboration.

This review discusses the diagnostic criteria and challenges in recognizing polycystic ovary syndrome, noting varied phenotypes and the absence of consensus on renaming the condition; it reports no new findings.

In this network meta-analysis, the researchers reported that topical minoxidil 5% was the most effective off-label therapy for increasing hair density in men with androgenetic alopecia, while other treatments like melatonin and cetirizine showed potential benefits, highlighting a need for further comparative trials.

This study introduced a novel microneedle-based system for androgenetic alopecia treatment, which delivered Ginsenoside Compound K and S-nitrosoglutathione to enhance hair regeneration by improving the hair follicle microenvironment and promoting follicular cell proliferation.

In this study, researchers developed a novel nucleic acid nanoparticle system incorporating quercetin, which they found enhances functional hair follicle regeneration and maintains epithelial structure stability in androgenetic alopecia by regulating hair follicle stem and dermal papilla cells.

This expert panel review developed consensus recommendations for managing androgenetic alopecia in Canadian adults, endorsing seven interventions like oral and topical medications and platelet-rich plasma.

This review found that exosome therapy shows the most promise for hair regrowth and safety in treating androgenetic alopecia, surpassing platelet-rich plasma, while minoxidil remains less effective but more accessible. Further research is needed to refine these treatments.

In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.

This study demonstrated that PGF 2α significantly stimulates hair growth in human hair follicles via a receptor-driven mechanism, with a notably stronger response in intermediate follicles than in terminal ones, suggesting potential clinical significance for conditions like alopecia.

This study observed that six sessions of injections using a stabilized hyaluronic acid compound improved hair thickness, shine, density, and reduced hair loss in volunteers with moderate androgenetic alopecia, with excellent treatment tolerability and high satisfaction reported by 88.5% of participants.

This review focuses on the pharmacological properties, indications, contraindications, and safety profile of bicalutamide, a non-steroidal androgen receptor antagonist, in dermatological research, particularly its off-label use for improving female pattern hair loss as measured by Sinclair grading.

This review discusses current and emerging therapies for androgenetic alopecia, emphasizing regenerative treatments and nanotechnology advancements, but it reports no new clinical results.

This study reported that in laboratory conditions, a cell-free supernatant of Bifidobacterium longum BB536 promoted human dermal papilla cell proliferation and reduced damage and apoptosis caused by dihydrotestosterone, suggesting potential use as a preventative treatment for androgenic alopecia by modulating specific signaling pathways.

This study found that combining platelet-rich plasma therapy with topical minoxidil improved hair shaft diameter and hair follicle density more effectively than PRP alone in men with androgenetic alopecia.

In this study, Brazilian postmenopausal women reported that menopause significantly deteriorates the quality of their skin, nails, and hair, negatively affecting self-esteem and quality of life, with a need for better understanding of hormone replacement therapy's dermatological effects.

This review provides an overview of clinically approved small molecule drugs targeting androgen receptors and discusses therapeutic applications, without presenting new experimental results.

This review discusses acupuncture and moxibustion for alopecia and reports evidence suggesting their efficacy for various types of hair loss, but notes barriers like cost and aversion to needles.

This article discusses a combination of photobiomodulation and microneedling as a four-week treatment for male androgenetic alopecia in a case series, but reports no new clinical results.

This review discusses the challenges and research gaps in transgender health care, highlighting the need for dedicated research infrastructure and funding to develop a more comprehensive evidence base.

This source provides a comprehensive guideline for the management of transgender individuals in India, highlighting the need for multidisciplinary diagnosis, counseling for gender-affirming hormone therapy, and the importance of addressing social stigma, legal issues, and medical training to improve healthcare access for this population.

This article reviews various medical treatments for hidradenitis suppurativa based on the author's experience with over 350 patients, but it reports no new clinical findings.

This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.

This review concluded that botulinum toxins have various potential off-label uses for dermatological conditions, but further research is needed to fully establish their efficacy and safety in these applications.

Effective vaccines and treatments are crucial for long-term COVID-19 control.

This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.

This study found no clinically significant effects of intraovarian injection of platelet-rich plasma on ovarian function over one year in patients with extremely low functional ovarian reserve.

This study found that enhanced neurosteroid synthesis likely mediated by the translocator protein contributed to the anticonvulsant action of midazolam in mice.

This review highlights the potential of nano-phytopharmaceuticals in improving the bioavailability and efficacy of phytochemicals for treating locomotor, dermal, reproductive, and urinary tract disorders, but notes that more clinical and preclinical research is needed to establish their safety and efficacy for human use.