July 2023 in “International Journal of Endocrinology” In this study, researchers observed that Centratherum anthelminticum seed extract effectively reduced cholesterol, triglycerides, insulin resistance, and inflammatory markers, while normalizing hormone levels and oxidative stress markers in rodents with PCOS, suggesting potential benefits for managing the condition.
319 citations
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March 2023 in “Science Advances” This study demonstrated that a wearable bioelectronic patch with combined therapy significantly accelerated chronic wound healing in a rodent model by monitoring and treating wounds noninvasively.
August 2026 in “Pharmacological Research - Modern Chinese Medicine” This review reports that microneedle systems can enhance the delivery and effectiveness of Traditional Chinese Medicine compounds in treating skin disorders, though most findings are based on preclinical studies and face challenges in translating to clinical practice.
34 citations
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August 2005 in “Dermatologic Clinics” This review discusses how the brain can influence skin biology, suggesting a link between psychological factors and skin health, but it reports no new scientific findings.
124 citations
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January 2012 in “Journal of Allergy and Clinical Immunology” This study found that activation of cannabinoid 1 receptors in human scalp hair follicles may limit excessive mast cell activation and maturation, suggesting a potential therapeutic strategy for managing MC-dependent skin diseases.
37 citations
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January 2019 in “Dermatologic Therapy” This article is a letter to the editor discussing the treatment of telogen effluvium using a dietary supplement, but it provides no new research results.
32 citations
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October 2004 in “Experimental Dermatology” This study found that α-MSH acts as a modulator of inflammatory and fibrogenic responses in human fibroblastic skin cells, indicating potential therapeutic options for fibrotic skin disorders and inflammatory diseases of the hair follicle.
1 citations
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September 2004 in “Experimental Dermatology” This study found that α-melanocyte-stimulating hormone may modulate inflammation in skin connective tissue by inhibiting proinflammatory effects in fibroblasts.
1 citations
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January 2018 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that a herbal shampoo and solution were more effective than placebo in reducing hair loss and improving hair growth in participants with androgenetic alopecia and telogen effluvium.
In this study, exosomes were identified as influential in skin biology, demonstrating potential in accelerating wound healing by modulating inflammation and enhancing tissue regeneration, though their use remains primarily cosmetic pending FDA approval.
June 2026 in “International Journal for Research in Applied Science and Engineering Technology” This study formulated and evaluated a polyherbal hair growth oil using plants like Amla and Neem. The oil showed desirable physicochemical properties, stability, safety, and potential effectiveness, representing a promising natural alternative to synthetic hair care products for promoting healthy hair and scalp protection.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, researchers highlighted the potential of herbal hair oils made from rosemary (Rosmarinus officinalis) and black sesame (Sesamum indicum) as safe and effective alternatives to synthetic products, citing their antioxidant, anti-inflammatory, and nourishing properties that support scalp health and hair quality.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the potential of herbal hair oil prepared with rosemary and black sesame for scalp health, hair strength, and appearance, emphasizing their antioxidant and nourishing benefits as a natural alternative to chemical formulations.
January 2023 in “International journal of dermatology, venereology and leprosy sciences” This study found that patients with alopecia areata had altered levels of inflammatory and coagulation markers, suggesting an association with disease pathogenesis and potential predictive value.
September 2021 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” This study found that an ethanolic extract from the microalga Tetrathelmis tetrathele exhibited anti-inflammatory effects, promoted the proliferation of certain skin and hair cells, and inhibited 5α-reductase activity, suggesting its potential as a therapeutic agent for preventing alopecia and enhancing scalp health.
7 citations
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January 2022 in “Biomedicines” In this study, hair follicle-derived mesenchymal stromal cells showed potential for immunomodulation, with equivalent or superior responses compared to those from adipose tissue, suggesting a promising alternative cell source.
434 citations
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October 2003 in “PTR. Phytotherapy research/Phytotherapy research” This review discusses the use of natural products in cosmetic preparations for skin and hair care, but reports no new research results.
6 citations
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December 2017 in “Journal of Drug Delivery and Therapeutics” This article proposes the development of a non-sticky Arnica Hydrogel for hair growth, noting that current hair loss treatments do not provide satisfactory results.
May 2026 in “Iconic Research and Engineering Journals” This review concluded that polyherbal hair oils, using key medicinal plants, may offer a validated and sustainable alternative to synthetic cosmetics for hair and scalp health, with potential for industrial standardization and clinical use.
April 2026 in “Journal of Natural Remedies” This review presents a comprehensive evaluation of eleven traditional herbs, detailing their phytochemical properties, mechanisms, pharmacokinetics, and potential roles in managing alopecia, positioning them as holistic alternatives to conventional treatments like minoxidil and finasteride.
May 2025 in “International Ayurvedic Medical Journal” In this case report, a 19-year-old male with alopecia areata showed complete relief from symptoms and increased hair density after 90 days of Shamana therapy, suggesting its potential effectiveness in treating this condition with minimal side effects.
December 2023 in “Medicine and Materials” This study reviewed the use of essential oils in cosmetics and highlighted that while chamomile, rosemary, and geranium oils can be applied directly to the skin when diluted, most essential oils require caution due to potential dermatological reactions.
June 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a hydrogel containing extracts from azadirachta indica and tridax procumbens for treating seborrheic dermatitis, finding it passed various tests, including skin irritation and stability, suggesting potential future applications in herbal formulations.
This study found that while various cosmetic compounds are used for androgenetic alopecia, detailed understanding of their mechanisms of action for effective home treatment is lacking.
August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal” This study found that callus extracts from apple 'Hirosaki' may improve collagen synthesis, hair follicle cell proliferation, and possess significant anti-inflammatory properties.
39 citations
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January 2015 in “International journal for parasitology/International Journal for Parasitology” This study found that Schistosoma mansoni cercariae stimulate epidermal keratinocytes in mice, initiating pro-inflammatory responses and barrier repair mechanisms akin to those in wound healing.
2 citations
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May 2023 in “Frontiers in immunology” This review highlights advances in understanding inflammatory memory in epidermal stem cells, focusing on their capacity to remember prior inflammatory responses and respond more quickly to future stimuli, potentially aiding strategies against skin-related diseases.
7 citations
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April 2023 in “Biomedicines” This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.
5 citations
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July 2017 in “Molecular Medicine Reports” This study observed that ethanol extracts of Lygodium japonicum spores significantly reduced inflammatory responses in LPS-stimulated murine macrophages in vitro by negatively regulating p38 MAPK and NF-κB.
1 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.