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New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

Patients with acne vulgaris have lower serum irisin levels.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.

Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Environmental pollutants can damage hair health and cause hair loss.

Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

RANK-RANKL signaling is essential for hair growth and skin health.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.

Minoxidil promotes hair growth by increasing cell division and DNA synthesis.

The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Foxn1 is important for fat development, metabolism, and wound healing in skin.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Autophagy changes the protein makeup of hair.

Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.