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Blocking β-catenin in skin cells improves hair growth during wound healing.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Inhibiting class I HDACs helps maintain hair growth ability in skin cells.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Innovative methods are reducing animal testing and improving biomedical research.

The exact identity of skin stem cells and how skin cells differentiate is not fully known.

People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.

Specialized ribosomes affect aging in human skin cells.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Hair follicle regeneration needs special conditions and young cells.

Androgens prevent hair growth by changing Wnt signals in cells.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Macrophages help hair growth after injury through CX3CR1 and TGF-β1.