3 citations
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January 2019 in “Skin Appendage Disorders” This review of 32 articles suggests a stronger association between alopecia areata and allergic rhinitis than asthma in both adults and children, indicating a potential Th2-mediated component.
September 2025 in “Frontiers in Immunology” This review examines the interconnected processes of atopic dermatitis and alopecia areata, highlighting shared immune imbalances, genetic factors, and microbiome influences, while analyzing current and emerging treatments and identifying gaps in understanding these overlapping conditions.
March 2025 in “Journal of Education Health and Sport” This review, drawing on scientific literature, explores alopecia areata's pathogenesis and treatment, noting that while therapies like JAK inhibitors show promise, there remains a significant need for more effective and targeted solutions, and a better understanding of the disease mechanisms.
January 2025 in “Frontiers in Medicine” This study reviews the role of hair follicles in the development, symptoms, and treatment options for vitiligo and alopecia areata, aiming to enhance understanding of their involvement in these autoimmune conditions and explore potential therapies.
December 2024 in “Frontiers in Genetics” This review discusses the genetic causes and pathogenesis of Olmsted syndrome, emphasizing the potential for a genotype-phenotype correlation due to TRPV3 mutations, and explores avenues for individualized treatment developments for this condition.
January 2024 in “International journal of homoeopathic sciences” This abstract discusses alopecia areata, highlighting its complex autoimmune pathogenesis involving immune cells and signaling molecules, and underscores the importance of accurate diagnosis and tailored management strategies, noting the need for further research to improve treatments.
January 2020 in “Dermatology Review” Early diagnosis and treatment are crucial for managing alopecia areata, morphea, and psoriasis.
1 citations
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April 2015 in “Journal of Dermatology and Dermatologic Surgery” This study found higher serum prolactin levels in patients with psoriasis, vitiligo, and alopecia areata compared to controls, and prolactin levels correlated with disease severity in psoriasis and alopecia areata but not vitiligo.
October 2021 in “Dermatology Reports” This study found that serum IL-17A levels were significantly higher in patients with alopecia areata compared to healthy controls and correlated with disease severity and activity.
106 citations
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January 2013 in “Clinical and Developmental Immunology” This review discusses the pathogenesis of alopecia areata, highlighting the role of immune privilege collapse in hair follicles but reports no clinical results.
98 citations
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March 2019 in “Frontiers in immunology” This study concluded that heterozygous NFKB2 mutations lead to a distinct and severe form of primary immunodeficiency with early onset, primarily T cell-mediated autoimmunity, and impaired B-cell differentiation.
54 citations
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September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that vitamin A influences the immune response and hair cycle, affecting the progression of alopecia areata in mouse models.
46 citations
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November 2022 in “The Journal of Dermatology” This review discusses recent findings on the mechanisms driving bullous pemphigoid, highlighting epitope spreading and the roles of regulatory T cells, and reports no new experimental results.
37 citations
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January 2019 in “BioMed Research International” This review highlights that scalp pruritus is a complex condition with various underlying causes, making it a challenge to diagnose and manage effectively. It emphasizes the need for comprehensive patient evaluation, history-taking, and personalized treatment strategies to address quality of life impacts.
15 citations
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March 2020 in “Experimental and Therapeutic Medicine” This review discusses the inflammatory and immunological processes in the skin and reports no new clinical results, highlighting their roles in skin conditions like psoriasis, atopic dermatitis, vitiligo, and pemphigus.
4 citations
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October 2022 in “Genes” This review discusses the role of cutaneous and intestinal microbiota in the development of alopecia areata, summarizing current literature without reporting new clinical results.
3 citations
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September 2021 in “BioEssays” This article discusses a novel hypothesis on the role of hair follicles in dandruff pathogenesis, focusing on immune response and inflammation due to scalp microbiota changes and sebum by-products, but reports no new clinical results.
2 citations
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July 2022 in “Frontiers in Medicine” This review discusses the current understanding of frontal fibrosing alopecia's pathogenesis, highlighting genetic susceptibility, immune response involvement, and possible links to steroid hormones, but reports no new clinical results.
March 2026 in “Biomedicines” This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.
This article hypothesizes that thymoma with aplastic anemia may result from abnormal autoimmune CD8+ T lymphocytes produced by the thymoma, potentially leading to other cytotoxic T-cell-mediated autoimmune diseases.
6 citations
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July 2021 in “Bulletin of the National Research Centre/Bulletin of the National Research Center” This review discusses the transmission and immune response of SARS-CoV-2 and highlights ongoing research for developing vaccines and antiviral treatments, but it presents no new clinical findings.
466 citations
,
June 2009 in “Experimental dermatology” This review discusses recent advances in understanding acne pathobiology, highlighting the potential for developing new customized therapies, but it reports no new clinical findings.
112 citations
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January 2013 in “Experimental dermatology” This article offers a viewpoint on hidradenitis suppurativa pathogenesis, suggesting that impaired Notch signalling from γ-secretase mutations may drive inflammation and link the condition to other Th17-driven diseases.
68 citations
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January 2022 in “International Journal of Molecular Sciences” This review summarizes factors involved in polycystic ovary syndrome pathogenesis and management, highlights commonly prescribed and repurposed medications, and calls for well-designed clinical trials to evaluate these treatments further.
14 citations
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January 2019 in “PubMed” This review examines the potential roles of vitamin D in the pathogenesis of alopecia areata and suggests that vitamin D analogs like calcipotriol may have therapeutic potential.
10 citations
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December 2018 in “Internal Medicine” This study reports two cases of myasthenia gravis patients with thymoma who exhibited various autoimmune symptoms including alopecia, suggesting a link between thymus-related immune dysregulation and comorbid conditions.
8 citations
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October 2021 in “Stem Cell Research & Therapy” This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.
1 citations
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May 2025 in “Clinical Reviews in Allergy & Immunology” 1 citations
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March 2024 in “International journal of molecular sciences” This review discusses how ionizing radiation causes skin damage by inducing cellular senescence in keratinocytes, which secrete inflammatory mediators, recruiting immune cells and exacerbating inflammation, impacting the skin barrier function and healing.
January 2025 in “BioMed Research International” This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.