The Immunological Association Between Alopecia Areata and Respiratory Diseases: A Systematic Review

    January 2019 in “ Skin Appendage Disorders
    Calvin T. Sung, Franchesca Choi, Margit Juhász, Natasha Atanaskova Mesinkovska
    TLDR People with alopecia areata may also have allergic rhinitis and should be checked for respiratory allergies.
    The systematic review examined the immunological association between alopecia areata (AA) and respiratory diseases, focusing on atopic conditions. Analysis of 32 articles revealed a stronger association between AA and allergic rhinitis compared to asthma in both adults and children. The study suggested that AA might have a Th2-mediated immunological component, challenging the traditional Th1/Th2 paradigm. This association indicates that patients with AA should be further evaluated for atopic respiratory diseases, potentially guiding new targeted therapies.
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