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Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Targeting the skin's endocannabinoid system could help treat skin disorders.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Dog skin with hair loss, when transplanted to mice, regrew hair, suggesting the hair loss cause is likely body-wide, not skin-specific.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.

Pregnancy can cause various skin changes, including pigmentation, acne, and stretch marks, and may affect preexisting skin conditions.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Higher stress levels are linked to more skin problems, especially in young women.

Athletes need effective management of skin disorders for their performance and well-being.

Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.