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This study highlights the role of platelets in immune interactions and severe adenovirus infection, noting that activated platelets have a shorter lifespan. Results suggest potential for developing therapies targeting platelet senescence and immunologic mechanisms.

This study found that TNC + fibroblasts are crucial in neuro-immune interactions in various skin diseases, particularly inflammation and tumors, by engaging extensively with immune cells and overexpressing inflammatory genes, suggesting their significant role in skin abnormalities.

In this review, the researchers highlight the role of fibroblasts in regulating the extracellular matrix and immune responses, emphasizing the impact on macrophages and potential therapeutic insights for fibrotic diseases and cancer.

This review discusses the role of stress mediators in skin diseases and reports no new clinical results; the authors suggest further research in skin psychoneuroimmunology.

This article discusses the potential of extracellular vesicles for developing precise psychiatric therapies and the need for interdisciplinary collaboration, but reports no new clinical results.

This review explores the mechanisms of wound-induced hair follicle neogenesis in mice, discussing its potential to inform precision therapies for alopecia and scarless wound healing, but reports no new clinical results.

This study identified distinct myeloid subsets in the scalp of men with androgenetic alopecia, potentially revealing new drug targets for treatment.

This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.

Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.

This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.

The study investigated immune cell patterns around the hair follicle infundibulum in androgenetic alopecia, revealing significant differences in immune signatures between patients with AGA and control donors, specifically noting an enrichment of CD4 cells in the patient group.

This review discusses the interactions between immune cells and the skin epithelium and their impact on maintaining barrier function, emphasizing the potential to enhance epithelial barrier function in inflammatory diseases.

This study used digital-light-processing bioprinting to create a 3D skin-on-a-chip model with a miniaturized vascular network to closely study immune cell interactions similar to real human skin, demonstrating the potential to analyze immune-T cell trafficking influenced by skin signals.

Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.

This review article examines recent studies on the role of diverse immune cells in forming an active niche for hair follicles, offering new insights into hair growth and related diseases.

This study examined interactions between immune cells and dermal papilla cells in a patient with alopecia areata using single-cell RNA sequencing; it identified specific T cell subtypes and ligand-receptor pairs that may contribute to hair cycle disruption through inflammation.

This study examined recent findings on the role of host-microbiome interactions in acne, highlighting that the skin's microbiome composition differs between acne-affected and healthy individuals and discussing emerging microbiome-based treatments.

This review discusses the role of sex hormones in COVID-19 severity and reports no new clinical results; the authors suggest further research for gender-based personalized treatment options.

This study analyzed gene expression data to identify key genes involved in severe forms of alopecia areata, discovering four immune monitoring genes (LGR5, SHISA2, HOXC13, S100A3) with potential for early diagnosis and better understanding of the disease's biological mechanisms.

In this study, researchers identified genetic factors associated with frontal fibrosing alopecia, noting a protective effect of a specific CYP1B1 gene variant, which may offer insights into the disease's pathogenesis and future risk mitigation strategies.

Certain genetic factors may contribute to frontal fibrosing alopecia in Brazil.

This review examines the interaction between the extracellular matrix and immune cells in skin diseases and evaluates advanced therapies that target involved molecular mechanisms, reporting no new clinical findings.

In this study, researchers developed a predictive model for the onset of alopecia areata by analyzing six datasets to identify key feature genes and employing various machine learning algorithms, ultimately finding the XGBoost model most effective for clinical application.

This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

This pilot study suggests that lovastatin may counteract stress-induced MICA expression in hair follicles and enhance MICA shedding, potentially offering a complementary approach for alopecia areata treatment.

This review discusses how macro-environmental factors such as intradermal adipose tissue and sex hormones influence hair and feather stem cell niches, suggesting environmental targets for regenerative medicine, but reports no new clinical results.

This source discusses how the skin mycobiome, dominated by Malassezia fungi, may provide a unique niche that can be disrupted by environmental changes, potentially leading to the fungal pathogen C. auris overtaking Malassezia and predisposing individuals to severe infections.