The Manipulation of the Cedrol Metabolism Pathway by Baricitinib and Its Immune Interaction Mechanism Against Chemotherapy-Induced Alopecia

    May 2026 in “ Bioorganic Chemistry ”
    Tao Li, Liyan Lv, Yifei Zheng … Yuqing Zhao
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    Research cited in this study 16

    1. Oxyresveratrol Enhances Hair Regeneration in Human Dermal Papilla Cells and Androgenetic Alopecia Mouse Model Scientific Reports · 2025
    2. Cedrol in Ginger (Zingiber Officinale) as a Promising Hair Growth Drug: The Effects of Oral and External Administration on Hair Regeneration and Its Mechanism Bioorganic Chemistry · 2024
    3. Application of Baricitinib in Dermatology Journal of inflammation research · 2022
    4. Efficacy and Safety of the Oral Janus Kinase Inhibitor Baricitinib in the Treatment of Adults with Alopecia Areata: Phase 2 Results from a Randomized Controlled Study Journal of The American Academy of Dermatology · 2021
    5. Hair Growth Promoting Activity of Cedrol Nanoemulsion in C57BL/6 Mice and Its Bioavailability Molecules · 2021
    6. Human Placenta Induces Hair Regrowth in Chemotherapy-Induced Alopecia via Inhibition of Apoptotic Factors and Proliferation of Hair Follicles BMC Complementary Medicine and Therapies · 2020
    7. Herbal Preparations for the Treatment of Hair Loss Archives of Dermatological Research · 2019
    8. Hair Growth Promotion Effect of Cedrol Cream and Its Dermatopharmacokinetics RSC Advances · 2018
    9. Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia Medicinski arhiv · 2018
    10. The Role of Oxidative Stress in Early-Onset Androgenetic Alopecia Journal of Cosmetic Dermatology · 2016
    11. Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice Environmental Toxicology and Pharmacology · 2016
    12. Hair Growth Promoting Activity of Cedrol Isolated from the Leaves of Platycladus Orientalis Biomedicine & Pharmacotherapy · 2016
    13. Topical Curcumin Promotes Induction of the Murine Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2016
    14. Oxidative Stress in Alopecia Areata: A Case-Control Study American Journal of Clinical Dermatology · 2013
    15. 6-Gingerol Inhibits Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice PLOS ONE · 2013
    16. Topical Application of Cyclosporin A Induces Rapid Remodeling of Damaged Anagen Hair Follicles in Cyclophosphamide-Administered Mice Journal of Dermatological Science · 2001