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The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

miR-486 may help prevent hair loss in alopecia areata.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Caspase-7 has functions in skin and hair that are not related to cell death.

LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.

Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

ECM1-modified stem cells can effectively treat liver cirrhosis.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Advanced human skin models improve drug development and could replace animal testing.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.

ULBP3 levels are higher in Tinea capitis patients and may help predict the disease's severity.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.

Fisetin may help treat psoriasis and reduce skin inflammation.