Fatal Autoimmunity Results from the Conditional Deletion of Snai2 and Snai3

February 2015 in “ Cellular immunology ”

Peter D. Pioli, Xinjian Chen, Janis J. Weis, John H. Weis

alopecia dermatitis autoantibodies regulatory T cell bone marrow transplantation

Studysummary This study found that deleting Snai2 and Snai3 genes in mice disrupts immune cell development, resulting in severe autoimmunity and early death due to the loss of immune tolerance.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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