33 citations
,
October 2016 in “Photomedicine and laser surgery” This review discusses the development of IPL devices, highlights their established cosmetic uses, such as treating vascular and pigmented lesions, and suggests potential expansion into more effective combination therapies.
48 citations
,
November 2018 in “Journal of dermatological treatment” In a study reviewing 291 patients with lichen planopilaris, findings revealed that women were more commonly affected than men, cyclosporine and methotrexate were most effective in achieving remission, and 5-alpha reductase inhibitors and systemic retinoids were particularly beneficial for frontal fibrosing alopecia.
2 citations
,
February 2024 in “Journal of the European Academy of Dermatology and Venereology” This study resulted in a draft version of the Patient‐Reported Impact of Dermatological Diseases measure, PRIDD, which includes 27 items refined from patient consensus and is now undergoing psychometric testing.
7 citations
,
June 2009 in “Journal of the European Academy of Dermatology and Venereology” This study found that in lichen planopilaris, the basement membrane zone of the hair follicles exhibited disrupted and discontinuous staining patterns, potentially contributing to scarring and irreversible hair loss.
9 citations
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October 2022 in “Journal of Molecular Neuroscience” This study reports a novel LSS gene mutation in an Egyptian family with alopecia intellectual disability syndrome 4, expanding the known clinical and genetic features of the condition.
37 citations
,
December 2014 in “Journal of Biomedical Informatics” This study introduced LabeledIn, a semi-automatic, human-reviewed catalog of drug-disease treatment relationships, highlighting the important role of human input in creating accurate and detailed drug indication resources.
37 citations
,
October 2015 in “Anais Brasileiros de Dermatologia” This study found diverse clinical presentations of lichen planopilaris, with classic lichen planopilaris being the most common, highlighting the importance of recognizing this variability for accurate diagnosis.
July 2025 in “Frontiers in Medicine” This study identified compound heterozygous mutations, c.1101del and c.736 T > A, in the LIPH gene responsible for causing autosomal recessive woolly hair in a child, with c.1101del being a novel frameshift mutation.
14 citations
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May 2018 in “Journal of the American Academy of Dermatology” This paper reviews treatments for lichen planopilaris, including low-level laser therapy, but reports no new clinical results and highlights the need for further research.
18 citations
,
May 2006 in “Journal of Cutaneous Medicine and Surgery” This study reports the first known case of linear lichen planopilaris following Blaschko's lines in a nonfacial region.
16 citations
,
May 2000 in “Endocrinology” This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.
1 citations
,
August 2021 in “Journal of Investigative Dermatology” ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.
2 citations
,
July 2025 in “Analytical Chemistry” This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.
3 citations
,
October 2020 in “Arthritis Care & Research” This review discusses the advancement and validation of outcome measures for pediatric systemic lupus erythematosus to improve disease monitoring and treatment precision but reports no new clinical findings.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
October 2021 in “The Egyptian Journal of Hospital Medicine” In this study, intralesional platelet-rich plasma was found to be a beneficial and safe treatment option for oral lichen planus, an inflammatory disease affecting the oral mucosa.
January 2025 in “International journal of research studies in biosciences” This abstract discusses the prevalence and forms of lichen planopilaris, a type of scarring hair loss, but reports no new clinical findings.
19 citations
,
July 2017 in “Clinical and experimental dermatology” This study provides one of the first descriptions of the demographic, clinical, and therapeutic characteristics of lichen planopilaris in Chilean adults, reporting that treatment usually reduced or halted disease progression.
This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.
5 citations
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July 2023 in “International Journal of Women’s Dermatology” This study reports that anifrolumab showed promising improvement in a case of refractory discoid lupus erythematosus, specifically enhancing skin lesions and promoting hair regrowth, suggesting potential as an effective therapy for severe cases.
11 citations
,
February 2020 in “Dermatology and therapy” This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.
10 citations
,
May 2020 in “Dermatologic therapy” In this study, a patient with recalcitrant lichen planopilaris and frontal fibrosing alopecia showed significant improvement after receiving four doses of the interleukin-23 monoclonal antibody tildrakizumab.
December 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that IL-1β may play a role in inflammatory signaling pathways in papulopustular rosacea, contributing to its pathogenesis.
April 2023 in “Journal of Investigative Dermatology” This study found that NIMP-R14-conjugated nanoparticles, loaded with roflumilast, effectively targeted neutrophils to reduce inflammation and improve symptoms in a mouse model of psoriasiform dermatitis, suggesting potential for targeted therapy in autoimmune skin diseases.
This study found that activating Toll-like receptor 3 signaling in periodontal ligament stem cells may enhance their immunomodulatory properties, suggesting potential implications for future stem cell therapy applications.
2 citations
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June 2020 in “Dermatology and therapy” In this case report, narrowband-UVB phototherapy successfully treated a rare instance of Graham Little-Piccardi-Lassueur syndrome, a variant of lichen planopilaris, as investigated through non-invasive imaging techniques.
April 2023 in “Journal of Investigative Dermatology” In this study, a mouse model of scarring alopecia demonstrated significantly reduced CD200R expression in affected skin, which may contribute to immune attacks on hair follicles.
5 citations
,
August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
2 citations
,
January 2024 in “Advances in Dermatology and Allergology” This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.
December 2023 in “Journal of General Procedural Dermatology and Venereology Indonesia” The abstract highlights that lichen planus can manifest as cicatricial alopecia or lichen planopilaris, while discoid lupus erythematosus, a common form of lupus erythematosus, typically causes scarring alopecia. Results are not reported here.