SnapshotDx Quiz: January 2021

    January 2021 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Umber Dube, Amy Musiek
    TLDR Papulopustular rosacea is an inflammatory skin condition treatable with lifestyle changes and medications.
    The "SnapshotDx Quiz: January 2021" from the Journal of Investigative Dermatology focused on diagnosing papulopustular rosacea (PPR), a chronic inflammatory condition. The study highlighted the role of IL-1β in PPR, showing that IL-1β treatment induced a transcriptional and proteomic signature of the disease in nonlesional skin. Researchers found upregulation of the MAPK and TNF signaling pathways in PPR skin explants. Treatment recommendations included avoiding environmental triggers, using gentle skin hygiene, and applying topical or oral medications like ivermectin, azelaic acid, and tetracycline antibiotics.
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