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GlossaryExtracellular Signal-Regulated Kinase (Mitogen-Activated Protein Kinase)

protein that transmits signals from cell surface to DNA

Extracellular Signal-Regulated Kinase (ERK) is a type of protein kinase that plays a crucial role in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway. It helps transmit signals from the cell surface to the DNA in the cell nucleus, influencing processes like cell division, differentiation, and survival. This pathway is important in various biological functions and can be implicated in conditions like cancer and alopecia when dysregulated.

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Phosphatidic Acid Has Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells

research Phosphatidic Acid Has Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells

46 citations, August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology”

Phosphatidic acid may help hair grow by affecting cell growth pathways.

Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

3 citations, July 2020 in “Frontiers in Cell and Developmental Biology”

Vitexin Compound 1 may help reduce skin aging caused by UVA light.

Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids

research Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids

1 citations, October 2022 in “Research Square (Research Square)”

Melatonin helps improve Cashmere goat hair quality by promoting hair follicle growth through a specific cell signaling pathway.

research Involvement of Activation of Mitogen-Activated Protein Kinase (MAPK)/Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway in Proliferation of Urethral Plate Fibroblasts in Finasteride-Induced Rat Hypospadias

10 citations, December 2018 in “Medical Science Monitor”

The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.

research LL-37 Stimulates the Functions of Adipose-Derived Stromal/Stem Cells via Early Growth Response 1 and the MAPK Pathway

53 citations, April 2016 in “Stem cell research & therapy”

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.