Basement Membrane Changes in Lichen Planopilaris

    Khitam Al‐Refu, Mark Goodfield
    Studysummary This study found that in lichen planopilaris, the basement membrane zone of the hair follicles exhibited disrupted and discontinuous staining patterns, potentially contributing to scarring and irreversible hair loss.
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    Research cited in this study 3

    1. Immunofluorescence Analysis of the Basement Membrane Zone Components in Human Anagen Hair Follicles Experimental Dermatology · 2003
    2. Cicatricial (Scarring) Alopecia: Clinical Presentations, Etiologies, and Histopathologic Features International Journal of Dermatology · 2001
    3. Elastic Tissue in Scars and Alopecia Journal of cutaneous pathology · 2000

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    2. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    3. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981