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Glossary Type I Collagen

most abundant protein in skin, bones, and tendons

Type I Collagen is the most abundant collagen in the human body, making up about 90% of the collagen found in skin, bones, tendons, and other connective tissues. It provides structural support and strength, playing a crucial role in wound healing and maintaining the integrity of various tissues.

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research Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle.

45 citations , August 1992 in “PubMed”

In this study, researchers found that changes in the extracellular matrix components, particularly fibronectin, laminin, and type IV collagen, during the rat vibrissa follicle growth cycle, suggest dynamic remodeling related to dermal-epidermal signaling.

research The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages

36 citations , January 2007 in “Archives of Histology and Cytology”

This study suggests that the absence of alpha5(IV)/alpha6(IV) chains in certain subepidermal basement membrane spots may relate to interactions with melanocytes in human skin.

research Expression of laminin, type IV collagen and fibronectin molecules is related to embryonal skin and epidermal appendage morphogenesis.

10 citations , January 2001 in “PubMed”

In this study, researchers found that the expression of laminin, collagen type IV, and fibronectin in fetal human skin begins in hair follicle germs and extends to epidermal cells by 21 weeks gestational age.

research Enrichment and characterization of human dermal stem/progenitor cells using collagen type IV

11 citations , June 2012 in “Journal of Dermatological Science”

This article reviews how aging affects skin and stem cells, but it contains no new research findings.

research Basement membrane Laminin and Type IV Collagen in Various Benign and Malignant Adnexal Tumors of the Skin: An Immunohistochemical Study

28 citations , October 1984 in “Journal of Investigative Dermatology”

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community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 2 years ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community “I’ll be happy as soon as fin brings my hair back” march 21, 2023

138 upvotes 1 year ago

The user is struggling with hair loss and has tried treatments like finasteride, minoxidil, and dutasteride without success, considering a hair transplant as a future option. Others suggest focusing on mental health and self-worth beyond physical appearance, while some share their own experiences with similar treatments and outcomes.

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58
Hair Transplant Surgeon
Dr. W. Patrick Coleman, IV, MD
Metairie, LA, United States