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    Glossary Type I Collagen

    most abundant protein in skin, bones, and tendons

    Type I Collagen is the most abundant collagen in the human body, making up about 90% of the collagen found in skin, bones, tendons, and other connective tissues. It provides structural support and strength, playing a crucial role in wound healing and maintaining the integrity of various tissues.

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    1. Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle. PubMed · 1992 · 45 citations
    2. The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages Archives of Histology and Cytology · 2007 · 36 citations
    3. Expression of laminin, type IV collagen and fibronectin molecules is related to embryonal skin and epidermal appendage morphogenesis. PubMed · 2001 · 10 citations
    4. Enrichment and characterization of human dermal stem/progenitor cells using collagen type IV Journal of Dermatological Science · 2012 · 11 citations
    5. Basement membrane Laminin and Type IV Collagen in Various Benign and Malignant Adnexal Tumors of the Skin: An Immunohistochemical Study Journal of Investigative Dermatology · 1984 · 28 citations
    6. Immortalized Rat Whisker Dermal Papilla Cells Cooperate with Mouse Immature Hair Follicle Buds to Activate Type IV Procollagenases in Collagen Matrix Coculture: Correlation with Ability to Promote Hair Follicle Development in Nude Mouse Grafts Journal of Investigative Dermatology · 1995 · 11 citations
    7. Induction of follicle formation and hair growth by vibrissa dermal papillae implanted into rat ear wounds: vibrissa-type fibres are specified Development · 1992 · 125 citations
    8. Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination Differentiation · 1990 · 56 citations
    9. A New Method for Culturing Human Hair Follicle Cells on Floating Mixed Collagen Membranes The Journal of Dermatology · 1990 · 6 citations
    10. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression Drug Design Development and Therapy · 2015 · 27 citations
    11. The 800-nm diode laser irradiation induces skin collagen synthesis by stimulating TGF-β/Smad signaling pathway Lasers in Medical Science · 2011 · 59 citations
    12. Design of an artificial skin. IV. Use of island graft to isolate organ regeneration from scar synthesis and other processes leading to skin wound closure Journal of Biomedical Materials Research · 1998 · 13 citations
    13. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression. PubMed · 2015 · 26 citations
    14. Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation Journal of Investigative Dermatology · 2003 · 56 citations
    15. Expression of basement membrane components through morphological changes in the hair growth cycle Developmental Biology · 1985 · 53 citations
    16. Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids Stem cell reports · 2022 · 14 citations
    17. Expression of extracellular matrix in hair follicle mesenchyme in alopecia areata British Journal of Dermatology · 1990 · 11 citations
    18. Basement membrane changes in lichen planopilaris Journal of the European Academy of Dermatology and Venereology · 2009 · 7 citations
    19. Effects of extracellular matrix on the growth characteristics of human dermal papillae cells<i>in vitro</i> Clinical and Experimental Dermatology · 2016 · 2 citations
    20. Effects of hyperbaric oxygen therapy on rat facial skin Human & Experimental Toxicology · 2015 · 2 citations
    21. Hair follicle micro-particle skin grafting induces scar remodeling via PI3K-AKT signaling: a randomized clinical trial npj Regenerative Medicine · 2026
    22. Alpaca<i> (Vicugna</i><i> pacos)</i> Skin Analyzed Under Architecture and Structure UNESP Institutional Repository (São Paulo State University) · 2024
    23. Acquired curved hair is caused by fusion of multiple hair matrix cells Journal of Dermatological Science · 2024
    24. 130 Expression of nidogen1 in basal cell carcinoma Journal of Investigative Dermatology · 2018
    25. MicroRNA 조절을 통한 상처 치유 기전에 관한 연구 2017
    26. Enrichment of human hair follicle stem cells by adhering to typeIVcollagen 2006
    27. Stem cell factor combined with matrix proteins promotes attachment and migration of amelanotic melanocyte from human follicle hair Linchuang pifuke zazhi · 2006
    28. The Function and Structure of the Skin 2014 · 4 citations
    29. Expression of the Orphan Protein Plet-1 during Trichilemmal Differentiation of Anagen Hair Follicles 2010 · 30 citations
    30. [Experimental study on vascular endothelial growth factor 165 gene-modified rat hair follicle stem cells mediated by lentiviral vector]. PubMed · 2014