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This study developed a composite hydrogel that delivered multiple proteins, enhancing skin wound healing by accelerating closure and promoting hair follicle regeneration.

This study found that a newly developed ultrasound-responsive hydrogel, incorporating ADSC-derived exosome nanobubbles, substantially improved wound healing in rats by enhancing skin closure, re-epithelialization, and hair follicle regeneration, while potentially reducing scar formation.

In this study, a hydrogel loaded with SHP099 was shown to improve wound healing by targeting different cell types during various stages of the healing process.

Disulfide bonds are crucial for hair structure during keratinization.

This study found that a dopamine-methacrylated hyaluronic acid hydrogel enhances the efficacy of adipose-derived stem cells in promoting skin regeneration, potentially involving the Notch signaling pathway.

This study explored the development of zinc-incorporated gelatin-based hydrogels, which demonstrated strong antibacterial properties and supported skin cell health, ultimately improving the healing process of S. aureus-infected full-thickness wounds, showing promise as wound dressings for infected wounds.

In this study, a hydrogel wound dressing infused with tannic acid demonstrated excellent antibacterial activity and promoted effective wound healing in rat burn models, leading to wound closure in 17 days and hair regrowth by day 21.

This study found that the carbohydrate-based excipient β-cyclodextrin forms a stable inclusion complex with the active ingredient of Minoxicapil®, potentially enhancing its formulation for hair-loss treatment, and in vitro assays suggest improved proliferation of DPC cells, supporting its use in topical treatments.

This study introduces a new biomimetic double wound mask designed to promote scarless healing by coordinating multiple biological pathways and providing enhanced protection and nourishment to wounds.

This study found that 3D-printed polyamine-modified hydrogels facilitate M2 macrophage polarization and exosome secretion, enhancing skin cell compatibility and promoting wound healing and hair follicle induction in an animal model through specific signaling pathways, suggesting potential for skin disorder therapies.

This study found that gelatin microspheres delivering adipose-derived stem cells significantly accelerated diabetic wound healing in rats, suggesting a promising approach for enhancing cell-based therapies.

This study demonstrates the use of microscopy-guided laser ablation to create a highly structured 3D hydrogel-based organotypic skin model with folliculoid structures, potentially useful for studying hair follicle development or bioactive substance screening.

In this study, the authors reported that combining PMSC-secretome and Wnt10b in a GelMA hydrogel scaffold promoted effective hair follicle biofabrication and hair growth in a small in vivo experiment. They emphasized the need for larger studies to confirm these results.

This research highlights advancements in reconstructive surgery for managing scars, emphasizing the importance of combined surgical and nonsurgical interventions like platelet-rich plasma and stem cell therapy to prevent and treat thick scar tissue while enhancing functionality and aesthetic outcomes.

New materials and methods could improve skin healing and reduce scarring.

This review discusses temporary chemical hair removal methods involving thioglycolates and other compounds but reports no new clinical findings; the authors highlight interest in natural-based substances.

This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.

This review concludes that exogenous hydrogen peroxide, rather than UV light, is likely the key factor in the development of cutaneous melanoma in swimmers, as it can penetrate water-submerged hair follicles.

This paper introduces a new understanding that the human hair follicle medulla lacks metabolic activity for H2O2 breakdown, indicating that H2O2 decomposition occurs primarily in the cortical areas.

This manuscript suggests that exogenous hydrogen peroxide is a primary risk factor for higher incidence of cutaneous melanoma in swimmers, with UV radiation playing a secondary role.

This study found that 3D cultured hair follicle-like constructs, which include keratinocytes and dermal papilla cells, showed improved gene expression and cell interactions relevant to hair follicle development.

In a mouse model of deep skin burns, this study found that a neuro-inspired biomimetic microreactor, when delivered through a hydrogel and activated by near-infrared light, significantly promoted functional skin regeneration, sensory recovery, and hair follicle formation.

This study developed thermo-reversible glycol chitosan hydrogels that effectively form and maintain 3D cell spheroids within one day, offering a simplified method for creating biologically realistic cultures for tissue regeneration and drug screening applications.

In this study, tubular 3D bioprinted structures made from sodium alginate and gelatin, containing NIH/3T3 fibroblast cells, demonstrated the ability for cell growth and network formation over 6 weeks, although structural tensile strength decreased with cell growth and polymer degradation.

This study characterized the crystal structures and supramolecular architectures of new salts made from 2,4-diaminopyrimidine and different dicarboxylic acids, revealing subtle differences in crystal packing and hydrogen-bonding patterns, particularly influenced by sulfur atom interactions, through Hirshfeld analysis and enrichment ratios.

This review reports that biomaterial-based drug delivery systems show promise in overcoming the limitations of traditional therapies for pathological scars by integrating sustained drug release with minimally invasive transdermal technologies, potentially enhancing treatment efficacy for these challenging skin lesions.

This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.

This study systematically analyzed the molecular and cellular mechanisms of wound healing and assessed the market potential for wound healing products based on natural proteins, projecting significant growth by 2033.

This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.

This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.