15 citations
,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” This study reported that combining microdialysis and selective follicular closure with varnish significantly reduces caffeine penetration through hair follicles in an ex vivo porcine ear skin model.
15 citations
,
November 2019 in “Cutaneous and Ocular Toxicology” This study investigated a liposomal hydrogel system for delivering minoxidil and tretinoin to treat androgenic alopecia, finding that the system enhanced skin permeation of minoxidil while retaining tretinoin on the skin and was non-irritating in animal tests, suggesting its potential effectiveness.
15 citations
,
January 2019 in “Mediators of inflammation” This study concluded that Aloe vera fermentation significantly accelerates burn injury healing in rats by reducing inflammation and altering gut microbiota composition.
15 citations
,
February 2017 in “Nursing Clinics of North America” This article reviews common skin reactions associated with epidermal growth factor receptor inhibitors and reports no new clinical findings, emphasizing the need for understanding nursing care and oncodermatology.
15 citations
,
March 2014 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This review discusses the role of acyl-CoA binding protein (ACBP) in the epidermal barrier, noting that its disruption in mice is linked to skin and fur abnormalities; it reports no new clinical results.
15 citations
,
February 2014 in “BMC Research Notes” This study found that male androgenic alopecia patients using the X5 hair laser device showed a statistically significant increase in hair growth over a 26-week period.
15 citations
,
October 2012 in “InTech eBooks” Niosomes are a promising and effective way to deliver drugs through the skin.
15 citations
,
March 2012 in “British journal of dermatology/British journal of dermatology, Supplement” This review discusses the role of shaving technology and specific skincare ingredients like glycerine and niacinamide in improving male facial skin health, but reports no new clinical results.
15 citations
,
January 1988 in “Drugs” The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.
14 citations
,
January 2025 in “AAPS PharmSciTech” This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.
14 citations
,
February 2021 in “International Journal of Pharmaceutics” In this study, applying deer antler velvet extract-loaded niosomes and microspicules serum to the scalp significantly improved hair growth, melanin content, and skin hydration over 14 to 30 days without causing skin irritation.
14 citations
,
January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
14 citations
,
February 2020 in “Scientific reports” This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.
14 citations
,
July 2016 in “Environmental Toxicology and Pharmacology” In this animal study, cedrol treatment reduced chemotherapy-induced alopecia in mice by preventing hair follicle damage, while minoxidil did not prevent alopecia under similar conditions.
14 citations
,
December 2011 in “Archives of Dermatological Research” This study found that phyto-vesicles of ß-sitosterol showed better absorption and improved activity for treating androgenetic alopecia in rats compared to the compound and its complex.
14 citations
,
October 2000 in “Genomics” This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.
14 citations
,
July 1987 in “Dermatologic Clinics” This article reviews current evaluation and treatment options for androgenic alopecia in women and reports no new clinical results.
13 citations
,
March 2022 in “Cell Death and Differentiation” This study found that while autonomous Sema3A expression limited keratinocyte migration and delayed wound healing, non-autonomous application of recombinant Sema3A with EGF enhanced wound repair in mice.
13 citations
,
August 2020 in “Frontiers in Cell and Developmental Biology” This study found that Twist1 and Tcf4 synergistically regulate the hair follicle induction ability of dermal papilla cells by forming a complex with β-catenin, enhancing their biological properties.
13 citations
,
January 2020 in “Nanoscale” Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.
13 citations
,
April 2019 in “American Journal of PharmTech Research” In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.
13 citations
,
September 2015 in “Aesthetic Surgery Journal” This article discusses the potential use of nape and peri-auricular hair for creating softer hairlines in transplants and reports no clinical results; the authors highlight concerns about their permanency.
13 citations
,
February 2015 in “Journal of Pharmaceutical Sciences” This study found that the polymorphic forms I, II, and III of finasteride can be prepared purely, with form III being identical to what was previously referred to as form X.
13 citations
,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
12 citations
,
April 2023 in “Nano Biomedicine and Engineering” This study synthesized silver nanoparticles using an Artocarpus heterophyllus leaf extract and found that these nanoparticles, with a size of 100–110 nm, displayed effective antioxidant, antibacterial, and antifungal activities in vitro.
12 citations
,
December 2022 in “Annals of Phytomedicine An International Journal” This review discusses the historical and potential medical uses of Cyperus rotundus rhizomes, but reports no new clinical results and emphasizes the need for further study on its pharmacognostic properties.
12 citations
,
June 2022 in “FARMACIA” This study found that a topical transethosomal system may enhance the skin penetration and deposition of naftifine compared to a marketed cream, potentially overcoming the stratum corneum barrier.
12 citations
,
June 2019 in “Psychoneuroendocrinology” This study found that in rodent models, the ability of D1 dopamine receptor activation to impair sensory gating is facilitated by 5α-reductase type 1, which produces allopregnanolone.
12 citations
,
February 2019 in “Skin research and technology” This study found that white hair fibers have lower lipid content and different water absorption dynamics compared to brown hair fibers, suggesting differences in their barrier functions.
12 citations
,
September 2018 in “Journal of Drug Delivery Science and Technology” This study found that a new hydrogel formulation of basic fibroblast growth factor showed promise in promoting hair regrowth and reducing inflammation in testosterone-treated mice.