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The exact causes of baldness are not fully understood, limiting treatment options.

New compounds may help treat prostate cancer by reducing cell growth.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Compound 4 is a promising treatment for hair loss with low toxicity.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Dutasteride is more efficient than finasteride, but individual results vary.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Certain drugs that block specific enzymes can help treat prostate diseases.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Gene differences may affect baldness treatment response in Korean men.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.