1308 citations,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
37 citations,
January 2013 in “Postepy Dermatologii I Alergologii” Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.
8 citations,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
78 citations,
August 2014 in “Anais Brasileiros de Dermatologia” New vitiligo treatments focus on controlling immune damage and restoring skin color.
11 citations,
November 2017 in “Hong Kong Medical Journal” Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
991 citations,
January 2011 in “Nature Reviews Endocrinology” The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
August 2023 in “Cell Proliferation” Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.
18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
24 citations,
July 2017 in “Structure” FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
70 citations,
December 2004 in “Differentiation” The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
3 citations,
May 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
13 citations,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
211 citations,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
97 citations,
September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
14 citations,
August 2018 in “Frontiers in Cellular and Infection Microbiology” Dengue virus can infect human hair follicle cells and may cause hair loss.
22 citations,
June 2013 in “Australasian Journal of Dermatology” Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
March 2024 in “Bioimpacts” 400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
2 citations,
December 2022 in “International journal of molecular sciences” Plucked hairs can be used instead of skin biopsies to study hair traits because they contain specific cells related to hair.
14 citations,
May 2022 in “Asian Journal of Pharmaceutical Sciences” New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
16 citations,
December 2016 in “Molecular Medicine Reports” Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.
July 2024 in “ACS Biomaterials Science & Engineering” Nanoencapsulated antibiotics are more effective in treating hair follicle infections than free antibiotics.
107 citations,
December 2013 in “International Journal of Dermatology” The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
27 citations,
August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found new genes involved in hair growth, which could help develop new hair treatments.
185 citations,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
2 citations,
May 2023 in “Plants” Allium hookeri extract may help promote hair growth and protect cells from damage.
4 citations,
July 2023 in “Pharmaceutics (Basel)” Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
2 citations,
August 2020 in “Clinical, Cosmetic and Investigational Dermatology” The hair-growth formula with L-cystine helps protect and grow hair cells.
11 citations,
June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.