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Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.

Hair follicle regeneration needs special conditions and young cells.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

Combining specific inducers helps dermal papilla cells regain hair-forming ability.

PRP and cell therapies may help with hair loss, but more research is needed.

Effective PCOS treatments require targeting specific signaling pathways.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Human scalp fat stem cells showed improved cartilage-like development on a special scaffold with freeze-thaw treatment.

Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.

MSC-protein helps regenerate gum tissue and bone.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Advanced human skin models improve drug development and could replace animal testing.

Fat cells in the skin help start healing and form important repair cells after injury.

Extracellular vesicles, including exosomes from certain cells, can stimulate hair growth.

Proteins from stem cells improved hair growth in patients with hair loss.

Both fat-derived stem cells and platelet-rich plasma are effective and safe for hair loss, but stem cells give better results with more side effects.

Stem cells could improve hair growth and new treatments for baldness are being researched.