29 citations
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February 2001 in “Proceedings of the National Academy of Sciences” This study found that the HS III element in the K14 gene's regulatory sequence promotes gene expression in inner root sheath keratinocytes, highlighting cooperative interactions in keratinocyte-specific gene regulation.
June 2024 in “British Journal of Dermatology” This article traces the historical development of hidradenitis suppurativa's naming and classification, noting that naming disagreements persist despite extensive research.
1 citations
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November 2013 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This article reviews the presentations from the First Symposium of Ichthyosis Experts in Spain, held to address the challenges in organizing care for ichthyosis patients, and reports no new clinical results.
41 citations
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April 2010 in “Gender Medicine” This review discusses the causes, clinical features, diagnostic approach, and treatment options for hirsutism in women, but reports no new findings.
30 citations
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September 2017 in “Environmental health perspectives” This study found that potential exposure to Corexit™ dispersants during the Deepwater Horizon cleanup was associated with increased respiratory, dermal, and eye irritation symptoms among responders both during the cleanup and up to three years later.
May 2015 in “Journal of The American Academy of Dermatology” A woman was injured by a hedgehog falling on her, causing skin lesions but no disease.
20 citations
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April 2021 in “Journal of Womens Health” This guideline provides evidence-based recommendations for prescribing testosterone therapy to women with hypoactive sexual desire disorder, noting a moderate therapeutic benefit but highlighting limited data and regulatory challenges.
195 citations
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May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.
September 2025 in “JCEM Case Reports” In this case report, a 46-year-old woman initially diagnosed with 21-hydroxylase deficiency congenital adrenal hyperplasia was later identified as having 3β-HSD2 deficiency after further investigation, highlighting the need for awareness of rarer CAH forms to prevent delayed diagnosis and insufficient treatment.
13 citations
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September 2022 in “Biomolecules” This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.
5 citations
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August 2021 in “Frontiers in Cell and Developmental Biology” This study found that DHEA along with osteogenic induction medium significantly promotes the osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells from older individuals.
63 citations
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March 2011 in “Clinical Endocrinology” This review examines the evaluation and management of hirsutism and hyperandrogenism in postmenopausal women and reports no new clinical findings.
18 citations
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January 2003 in “Gynecological Endocrinology” In this study, low-dose finasteride (2.5 mg/day) significantly reduced hirsutism scores in women over 12 months without significant hormonal changes or serious side effects.
24 citations
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June 2021 in “Annals of Translational Medicine” This review discusses the potential of human placental extract (HPE) in cartilage regenerative medicine for osteoarthritis, noting its significant anti-inflammatory and regenerative properties observed in vitro and in vivo studies, but reports no new clinical results.
May 2024 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” This study aimed to determine the phenolic compound composition in Equisetum arvense stem extracts using HPLC, as the plant is commonly used in cosmetics for skin and hair care, but results are not reported here.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” This review explores the potential of selective 11β-HSD1 inhibitors to improve insulin sensitivity in type 2 diabetes, emphasizing the need for more clinical research and reports no new clinical results.
October 2025 in “Nepal Journal of Dermatology Venereology & Leprology” This study concluded that polycystic ovary syndrome is the most common cause of hirsutism, with significant correlations between PCOS, insulin resistance, and BMI among affected women.
September 2021 in “Fertility and sterility” In this study, daily administration of 100mg DHEA for 16 weeks in women with adequate ovarian reserve did not modify metabolic or reproductive variables, apart from increased antral follicular count and anti-Müllerian hormone levels.
46 citations
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August 2006 in “PubMed” In this study, researchers identified and examined males with 17 beta-HSD3 deficiency in a highly inbred Arab population, noting genetic findings and the progression of male characteristics despite being raised as females initially.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.
3 citations
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August 2022 in “Pharmaceuticals” This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
19 citations
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August 2018 in “JAMA dermatology” This study found that skin mesenchymal stem cells from hidradenitis suppurativa patients overexpress proinflammatory and anti-inflammatory cytokines, suggesting their potential contribution to the disease's pathogenesis.
3 citations
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May 2025 in “Clinical Endocrinology” Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study's new single-cell atlas of hidradenitis suppurativa tunnels identifies distinct fibro-inflammatory microenvironments, suggesting that TNF blockade may not address the primary pathway in many lesions.
July 2024 in “Journal of Investigative Dermatology” Sex and race affect immune responses and treatment outcomes in Hidradenitis suppurativa.
4 citations
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March 2021 in “Journal of Histotechnology” In this study, researchers observed that hidradenitis suppurativa lesions were associated with reduced collagen and elastin, and increased neovascularization in areas with chronic inflammation.
41 citations
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June 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.
19 citations
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October 2021 in “Medicine” In this study, anemia was commonly observed in exercising women, especially those with heavy menstrual bleeding, and the authors recommend using a simple screening tool involving haemoglobin testing.
4 citations
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September 2015 in “Bulletin of the Korean Chemical Society” This study presents a new method using UPLC-ESI-MS/MS for analyzing the constituents of a medicinal herbal complex extract, which includes herbs traditionally used to prevent hair loss and promote hair growth; no clinical results were reported.
19 citations
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March 1994 in “Fertility and sterility” This study found that treatment with a GnRH agonist and estrogen and progestin replacement significantly improved hirsutism scores and hair growth rates in women with polycystic ovarian disease.