Metabolic, Reproductive Outcomes and Side Effects After the Administration of 100 mg Dehydroepiandrosterone (DHEA) in Women with an Adequate Ovarian Reserve

    September 2021 in “ Fertility and sterility
    Mauricio Rangel
    TLDR Taking 100 mg of DHEA daily for 16 weeks did not change metabolic and reproductive health significantly but increased certain ovarian markers with minimal side effects.
    In a self-controlled study of 27 women aged 29 to 45 with an adequate ovarian reserve, the administration of 100 mg of DHEA daily for 16 weeks showed no significant changes in metabolic and reproductive variables, except for an increase in antral follicular count and anti-Müllerian hormone levels. The study found no significant side effects, with only one case of acne reported. The findings suggest that DHEA at this dosage is safe for women who are candidates for assisted reproductive techniques.
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