Exploring the Clinical and Investigational Profile of Females With Hirsutism at a Tertiary Care Center
October 2025
in “
Nepal Journal of Dermatology Venereology & Leprology
”
TLDR PCOS is the main cause of hirsutism, often linked to insulin resistance.
The study conducted at a tertiary care hospital over 2 years involved 43 women with hirsutism, revealing that Polycystic Ovary Syndrome (PCOS) was the most common cause, followed by idiopathic hirsutism. The study found that 65.11% of participants had mild hirsutism, 25.58% had moderate, and 9.30% had severe hirsutism. Menstrual irregularities were present in 58.14% of the women, and 46.51% exhibited insulin resistance, significantly correlated with BMI (p = 0.001). Additionally, 39.53% had an LH/FSH ratio >2, and 46.5% showed polycystic ovarian morphology. The findings emphasize the importance of assessing metabolic components like insulin resistance to identify the root cause and tailor interventions for hirsutism.