Clinical and Investigative Study of Hirsutism

    January 2019 in “ JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH ”
    Vaishali Wankhade, Vrutika H Shah, Suyash Singh Tomar, Rajesh Singh
    This study investigated the causes and characteristics of hirsutism in 50 female patients, finding that idiopathic hirsutism was the most common cause (40%), followed by PCOS (32%), HAIR-AN syndrome (16%), hypothyroidism (8%), and late-onset CAH (4%). Associated symptoms included acne (40%), female pattern hair loss (26%), and acanthosis nigricans (20%). Significant findings included elevated serum LH and LH:FSH ratio in PCOS and CAH, and increased serum 17-OH progesterone in CAH. The HAIR-AN group showed significant differences in waist circumference, serum fasting insulin, and HOMA-IR, highlighting the need to assess insulin resistance in hirsutism patients with acanthosis nigricans for appropriate management.
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