Clinico-Investigative Profile of Patients with Hirsutism in a Tertiary Level Institution

    January 2012 in “ International Journal of Trichology ”
    Divya Sharma, Vinay Shanker, Gitaram Tegta, Mrinal Gupta, Ghanshyam Verma
    Image of study
    TLDR Most hirsutism patients had idiopathic hirsutism or PCOS, with hormonal imbalances and signs like acne and irregular periods.
    The study conducted between August 2009 and July 2010 included 50 newly diagnosed hirsutism patients and found that idiopathic hirsutism (IH) was the most common cause, affecting 60% of patients, followed by polycystic ovarian syndrome (PCOS) in 38%. The mean age of participants was 23.8 years, and the modified Ferriman Gallwey (mF-G) score was used for clinical assessments. Hormonal analysis indicated higher levels of total and free testosterone, and 17-hydroxyprogesterone in PCOS patients compared to those with IH. Additionally, 50.8% of patients had irregular menstrual cycles, with 64.2% of these patients diagnosed with PCOS. Acne was the most common sign of hyperandrogenism, present in 60% of patients, and obesity was observed in 20% of the study population. The study concluded that hirsutism could be a marker for underlying hormonal and systemic conditions, and while PCOS patients showed more signs of hyperandrogenism, a detailed investigative approach was necessary for the idiopathic group. The study's limitation was its small sample size, suggesting that a larger sample might lead to a lower cutoff for the mF-G score.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 24 results

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 5 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community AA and Hirsutism but T levels are normal

      in Female  8 upvotes 3 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  105 upvotes 3 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  117 upvotes 2 months ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

      community Does low HGH leading to hairloss?

      in Research/Science  13 upvotes 9 months ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

    Similar Research

    6 / 1000+ results