research What Is the Rationale for Androgen Therapy for Women?
Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
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research Generalized Hypertrichosis After Treatment With Topical Minoxidil
Too much topical minoxidil can cause excessive hair growth, but stopping treatment reverses it.
research Are There Temporal Subtypes of Premenstrual Dysphoric Disorder? Using Group-Based Trajectory Modeling to Identify Individual Differences in Symptom Change
The study found three different timing patterns of symptoms in women with premenstrual dysphoric disorder.
research Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Thyroid Receptor Agonists for the Treatment of Androgenetic Alopecia
Thyroid receptor agonists may treat male pattern baldness without harmful side effects.
research Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo
Glycine reduces skin pigmentation by lowering melanin production.
research Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
Substance from human umbilical cord blood cells promotes hair growth.
research Unwanted Facial Hair: Effects and Solutions
Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region and Hair Bulb Area in Chronic Alopecia Areata Patients
Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
research Study on the Zona Pellucida 4 (ZP4) Gene Sequence and Its Expression in the Ovaries of Patients with Polycystic Ovary Syndrome
The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
research Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Visceral and Subcutaneous Adipose Tissues of Patients with Polycystic Ovary Syndrome Is Associated with Adiposity
Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study
Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
research Elevated Fasting Insulin Is Associated With Cardiovascular and Metabolic Risk in Women With Polycystic Ovary Syndrome
High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
research Cause of Androgenic Alopecia
Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.
research Erythropoietin Promotes Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice
Erythropoietin helps hair grow and could be a potential treatment for hair loss.
research Radiation-Induced Alopecia
A man experienced hair loss from radiotherapy, which can be temporary or permanent depending on radiation dose, with potential treatments available.
research Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production
A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
research Rapid Intravenous Administration of Corticotropin as a Test of Adrenocortical Insufficiency
The rapid corticotropin test is a quick and simple way to diagnose adrenal insufficiency.
research Hirsutism, Postpartum Telogen Effluvium, and Male Pattern Alopecia
Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
research Hair Growth Promoting Effect of Houttuynia Cordata Extract in Cultured Human Hair Follicle Dermal Papilla Cells
Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.
research Transgender Competent Provider
Healthcare providers need better education and policies to serve transgender individuals effectively.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Alopecia Areata in a Rhesus Monkey (Macaca Mulatta)
The monkey's hair loss was due to an autoimmune disease, not genetics.
research Telogen Effluvium Caused by Magnesium Valproate and Lamotrigine
Two people lost a lot of hair because of epilepsy drugs, but their hair grew back after changing medication.
research Post-Finasteride Syndrome: Risks and Side Effects of Finasteride for Androgenetic Alopecia
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
research Novel Uses for the Anabolic Androgenic Steroids Nandrolone and Oxandrolone in the Management of Male Health
Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
research Analysis of Genetic Polymorphisms of Steroid 5α-Reductase Type 1 and 2 Genes in Korean Men with Androgenetic Alopecia
Gene differences may affect baldness treatment response in Korean men.