Are There Temporal Subtypes of Premenstrual Dysphoric Disorder? Using Group-Based Trajectory Modeling to Identify Individual Differences in Symptom Change

    April 2020 in “ Psychological Medicine ”
    Tory A. Eisenlohr-Moul, Gudrun Kaiser, Cornelia Weise, Katja M. Schmalenberger, Jeff Kiesner, Beate Ditzen, Maria Kleinstäuber
    Image
    Studysummary This study identified three symptom trajectory groups in individuals with PMDD, highlighting variations in symptom severity and duration across the luteal and follicular phases. Our plain-language summary of this paper — not a Tressless recommendation.
    The study investigated premenstrual dysphoric disorder (PMDD) in 74 women, using group-based trajectory modeling to identify different patterns of symptom change over time. It found three distinct subtypes: one with moderate symptoms only in the premenstrual week (65% of the sample), another with severe symptoms throughout the luteal phase (17.5%), and a third with severe premenstrual symptoms that resolved slowly post-menses (17.5%). These findings suggest that PMDD has temporal subtypes, which could lead to more personalized treatment approaches. The study also noted that the early-onset PMDD group might be overrepresented in research due to their positive response to certain treatments. The research was funded by the National Institute of Mental Health and a Brain and Behavior Research Foundation Young Investigator Grant, and ethical standards for human experimentation were followed.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results