Telogen Effluvium Caused by Magnesium Valproate and Lamotrigine

    October 2004 in “ Acta dermato-venereologica ”
    Annalisa Patrizi, Francesco Savoia, Francesca Negosanti, Annio Posar, Margherita Santucci, Iria Neri
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    TLDR Two people lost a lot of hair because of epilepsy drugs, but their hair grew back after changing medication.
    The document reports two cases of telogen effluvium, a condition characterized by excessive hair loss, associated with the use of the anti-epileptic and mood-stabilizing drugs magnesium valproate and lamotrigine. In the first case, a 16-year-old girl experienced severe hair loss after starting a new course of magnesium valproate, which she had previously taken without side effects. The hair loss ceased and significant regrowth occurred after switching to lamotrigine. In the second case, a 24-year-old woman suffered chronic hair loss a few months after changing her medication to include magnesium valproate and increasing her dose of lamotrigine. The document suggests that patients who develop drug-induced hair loss may have a predisposition to the condition, which can be triggered by a change in therapy or new conditions. It also notes that alopecia may occur in up to 28% of patients using valproate at high doses and recommends starting with a low dose and gradually increasing it to minimize side effects.
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      in Progress Pictures  32 upvotes 1 year ago
      A 19-year-old male experienced significant hair loss, initially thought to be male pattern baldness (MPB), and used minoxidil and briefly finasteride. After realizing the issue was telogen effluvium (TE), he improved his diet and supplemented with vitamins, which led to substantial hair regrowth.

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      in Female  6 upvotes 6 months ago
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      in Finasteride/Dutasteride  51 upvotes 2 years ago
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      in Progress Pictures  72 upvotes 9 months ago
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