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Low dose finasteride causes only minor changes in PSA levels in men over 50 with BPH.

Low dose finasteride causes only small changes in PSA levels in older men with BPH.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Deleting MED1 in skin cells causes hair loss and skin changes.

A new tool can analyze hair to detect changes due to hormones, genetics, and aging.

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Hair loss caused by genetics and hormones; more research needed for treatments.

Targeting and modifying the stem cell niche can improve regenerative therapies.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

Dermal adipose tissue in mice can change and revert to help with skin health.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Male hormones worsen kidney transplant damage, but blocking them helps.

Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.

Different light affects cell functions and can help treat skin conditions.

The document suggests using natural remedies like bloodletting and honey for various health issues but lacks scientific evidence for their effectiveness.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.