Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that human trichohyalin has a unique protein sequence potentially contributing to at least three important functions in hair follicle and epidermal cells.

This study observed nestin-GFP expressing stem cells in the hair follicle bulge of living mice using high-resolution in-vivo multiphoton tomography, allowing migration tracking within their natural skin environment.

This study found that OCT4-overexpressing human hair follicle mesenchymal stem cells show promise for artificial hematopoiesis by enhancing self-renewal through cytoskeletal remodeling and the beta-catenin-dependent adherens junction pathway.

This study found that CLD-hFGF2 hydrogels improved healing in deep second-degree burn wounds more effectively than hydrogels alone or direct administration of CLD-hFGF2.

This study observed that human primary adult hair matrix keratinocytes may have the potential to generate hair follicle organoids, suggesting possible applications in hair follicle neogenesis and preclinical hair growth agent screening.

This review discusses the roles of filaggrin and trichohyalin in keratinocyte differentiation and reports no new results; the authors introduce possible hybrid granules in tongue epithelia.

In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.

This study found that hHbl gene expression is localized in the cortical cells of the human hair shaft and is notably high in pilomatricoma cells transitioning to hair shaft keratinocytes.

This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.

This study found that tyramine-linked hyaluronan gel effectively supports the 3-D culture of ovarian follicles, facilitating the maturation of functional metaphase II oocytes that can develop into blastocysts.

This study found that while hyaluronic acid fillers can enhance facial balance and aesthetics, particularly in the temple area, they carry significant risks like vascular occlusion and blindness, highlighting the need for careful technique and product selection to ensure safety.

This review details the development of the alpha-helix model for protein structure proposed by Pauling and Corey and confirms its validity through X-ray studies of myoglobin and lysozyme.

This review discusses the function and pathology of hair follicles and highlights the potential of using dogs as a model to study human hair and stem cell disorders, but presents no new experimental results.

This study suggests that reversible hypopigmentation in homocystinuric patients may result from tyrosinase inhibition by homocyst(e)ine, with in-vitro experiments showing copper sulfate reversing this inhibition.

This study evaluated a polyherbal hair oil made from natural ingredients and found that the F2 formulation demonstrated favorable physicochemical properties, good stability, and beneficial activities such as anti-dandruff, anti-hair fall, and hair growth promotion, identifying it as optimal for herbal hair care applications.

This review discusses recent advancements in hair follicle organoid technology for alopecia treatment but presents no new experimental results, emphasizing the potential for clinical applications and drug screening.

This study found that calanthoside, a compound isolated from Calanthe species, promotes the proliferation of human hair follicle dermal papilla cells more effectively than minoxidil.

Hair differentiation starts earlier than thought, involving multiple type-II keratins.

This study found that in human hair bulbs, telomerase is present mainly in the nuclei of cells undergoing proliferation, particularly in the matrix epithelium during the anagen phase, and sparsely in the outer root sheath during late catagen and telogen phases.

This study found that new folate salts in aqueous and lipophilic solutions can penetrate skin and enhance wound healing in vitro by converting metabolically, suggesting their potential for topical application.

This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.

This study demonstrated that novel cryomicroneedles loaded with hair follicle organoids (cryoMN@HFOs) can effectively deliver and develop into functional hair follicles after intradermal transplantation in animal experiments, suggesting promising potential for human hair follicle reconstruction.

This study found that forming solid dispersions and inclusion complexes of finasteride significantly increased its solubility compared to its pure form.

This study identified trichohyalin as an early differentiation marker in hair follicles, with potential structural roles related to alpha-helical formations, based on the partial characterization of its cDNA in sheep.

This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.

In this study, all stereoisomers of cyoctol were synthesized and tested, revealing that contrary to initial patent claims, cyoctol does not function as an anti-androgen.