Immunolocalization of Telomerases in Human Hairs Identifies Proliferating Cells in the Bulb Matrix and Outer Root Sheath

    March 2024 in “ Tissue and cell/Tissue & cell ”
    Lorenzo Alibardi
    Studysummary This study found that in human hair bulbs, telomerase is present mainly in the nuclei of cells undergoing proliferation, particularly in the matrix epithelium during the anagen phase, and sparsely in the outer root sheath during late catagen and telogen phases.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 7

    1. Expression and Localization of Sox10 During Hair Follicle Morphogenesis and Induced Hair Cycle International Journal of Medical Sciences · 2021
    2. Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices Cell · 2017
    3. Dissecting the Bulge in Hair Regeneration Journal of Clinical Investigation · 2012
    4. Conditional Telomerase Induction Causes Proliferation of Hair Follicle Stem Cells Nature · 2005
    5. A Review: The Location, Molecular Characterization and Multipotency of Hair Follicle Epidermal Stem Cells Annals of the Academy of Medicine Singapore · 2004
    6. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    7. Hair Follicle Companion Layer: Reacquainting an Old Friend ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1995

    Related research 7

    1. Keratin Microspheres As Promising Tool For Targeting Follicular Growth ACS applied bio materials · 2024
    2. Keratins of the Human Hair Follicle International review of cytology · 2005
    3. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    4. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003
    5. Expression of E6 and E7 Papillomavirus Oncogenes in the Outer Root Sheath of Hair Follicles Extends the Growth Phase and Bypasses Resting at Telogen PubMed · 2000
    6. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    7. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987